Safety and effectiveness of paravertebral block for simple mastectomy: a prospective study

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dc.contributor.authorHannan, MAen_US
dc.contributor.authorArin, KMen_US
dc.contributor.authorKarmakar, CSen_US
dc.contributor.authorTusher, SMen_US
dc.contributor.authorDas, RSen_US
dc.contributor.authorSultana, A.en_US
dc.date.accessioned2025-05-12T07:25:29Z
dc.date.available2025-05-12T07:25:29Z
dc.date.issued2024-09
dc.description.abstractBackground: Paravertebral block (PVB) has emerged as an alternative to general anesthesia (GA) for various surgical procedures, offering potential advantages such as improved postoperative pain control and reduced systemic side effects. Simple mastectomy, a common surgical intervention for breast cancer treatment, involves the removal of breast tissue without axillary lymph node dissection. Methods: This prospective study was conducted at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, from 1st January 2022 to 30th June 2023. A total of 50 patients undergoing simple mastectomy were randomly assigned. Results: PVB significantly reduced postoperative VAS scores at 1 hour (2.3�1 vs. 4.7�3), 6 hours (2.1�9 vs. 4.4�2), 12 hours (1.9�8 vs. 3.8�0), and 24 hours (1.7�6 vs. 3.5�9) (all p<0.001). Opioid consumption was lower in the PVB group (4.8�1 mg vs. 12.4�2 mg, p<0.001). Incidence of PONV was reduced (16% vs. 48%, p=0.019), hospital stay was shorter (2.3�5 days vs. 3.1�7 days, p=0.001), and patient satisfaction was higher (4.6�5 vs. 3.8�7, p=0.003). No significant differences were observed in intraoperative hemodynamic parameters or adverse events. Conclusions: Paravertebral block provides superior pain management, reduces opioid use and PONV, shortens hospital stays, and improves patient satisfaction compared to GA in simple mastectomy, demonstrating its efficacy and safety in perioperative care.en_US
dc.identifier.affiliationsDepartment of Anaesthesia, Analgesia and Intensive Care Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladeshen_US
dc.identifier.affiliationsDepartment of Anaesthesia, Analgesia and Intensive Care Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladeshen_US
dc.identifier.affiliationsDepartment of Anaesthesia, Analgesia and Intensive Care Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladeshen_US
dc.identifier.affiliationsDepartment of Anaesthesia, Analgesia and Intensive Care Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladeshen_US
dc.identifier.affiliationsDepartment of Anaesthesia, Analgesia and Intensive Care Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladeshen_US
dc.identifier.affiliationsDepartment of Anaesthesia, Analgesia and Intensive Care Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka, Bangladeshen_US
dc.identifier.citationHannan MA, Arin KM, Karmakar CS, Tusher SM, Das RS, Sultana A. . Safety and effectiveness of paravertebral block for simple mastectomy: a prospective study . International Journal of Research in Medical Sciences. 2024 Sep; 12(9): 3197-3202en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/246843
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber9en_US
dc.relation.volume12en_US
dc.source.urihttps://doi.org/10.18203/2320-6012.ijrms20242594en_US
dc.subjectGeneral anesthesiaen_US
dc.subjectOpioid consumptionen_US
dc.subjectParavertebral blocken_US
dc.subjectPostoperative painen_US
dc.subjectSimple mastectomyen_US
dc.titleSafety and effectiveness of paravertebral block for simple mastectomy: a prospective studyen_US
dc.typeJournal Articleen_US
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