Home-made rapid urease test compared with histopathologic examination for diagnosis of Helicobacter pylori infection (Home-made rapid urease test เทียบกับการตรวจทางพยาธิวิทยาสำหรับการวินิจฉัยการติดเชื้อ Helicobacter pylori)

dc.contributor.authorChatchawan Wongjitraten_US
dc.contributor.authorPiyanun Chonmitrien_US
dc.contributor.authorNattakarn Wongjitraten_US
dc.contributor.authorSomchai Santiwatanakulen_US
dc.date.accessioned2011-02-20T04:31:55Z
dc.date.available2011-02-20T04:31:55Z
dc.date.created2011-02-01en_US
dc.date.issued2011-02-01en_US
dc.description.abstractHelicobacter pylori is well established as the causative agent of gastric and duodenal ulcer gastritis gastric cancer and iron deficiency anemia. The detection of Helicobacter pylori infection can be performed easily by the rapid urease test (RUT) which has high sensitivity and specificity. However most commercial kits available in the market \ are expensive. To reduce the cost, HRH Princess Maha Chakri Sirindhorn Medical Center has produced the RUT kit for using in our own clinical laboratory. The purpose of this study was to evaluate sensitivity and specificity of home-made RUT compared with histopathologic examination. Cross sectional study of patients who underwent esophagogastroduodenoscopy and gastric biopsy was performed during June 2008 to May 2009. One-hundred and ninety-seven patients were included in the study. The sensitivity, specificity, positive and negative predictive values and accuracy of home-made RUT were 91.8%, 100%, 100%, 96.5% and 97.5%, respectively. Furthermore, 62% of the test showed positive results within 1 hour. In brief, our home-made RUT has good sensitivity and specificity for detection of Helicobacter pylori infection.en_US
dc.identifier.citationJournal of Medicine and Health Sciences; Vol 16, No 3 (2009): ปีที่ 16 ฉบับที่ 3 ธันวาคม 2552; 116-123en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/130759
dc.language.isoen_USen_US
dc.publisherJournal of Medicine and Health Sciencesen_US
dc.rightsJournal of Medicine and Health Sciencesen_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/JMHS/issue/archiveen_US
dc.source.urihttps://thailand.digitaljournals.org/index.php/JMHS/article/view/4415en_US
dc.titleHome-made rapid urease test compared with histopathologic examination for diagnosis of Helicobacter pylori infection (Home-made rapid urease test เทียบกับการตรวจทางพยาธิวิทยาสำหรับการวินิจฉัยการติดเชื้อ Helicobacter pylori)en_US
dc.typeOriginal Articleen_US
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