Bhallatakadi Ghrita: Development and evaluation with reference to Murcchana and Shata-Dhauta process

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dc.contributor.authorWayal, Sandesh R.en_US
dc.contributor.authorShailendra, S. Guraven_US
dc.date.accessioned2020-11-18T10:11:50Z
dc.date.available2020-11-18T10:11:50Z
dc.date.issued2020-07
dc.description.abstractBackground: Ayurveda is primarily based upon use of herbs either singly or in combination (polyherbal).The cow ghee (clarified butterfat) is considered as a precious base for preparing medicines in Ayurveda.Processing of ghee with plant ingredients is renowned for enhancing their therapeutic efficacy.Objective: In present research work, the attempt was made to develop cow ghee based PolyherbalBhallatakadi Ghrita formulations and evaluate them with reference to ‘Murcchana’ and ‘Shata-Dhauta’process.Materials and methods: The research plants were identified, procured, authenticated and processed. Theextracts of plant materials were prepared and used for development of Polyherbal Bhallatakadi Ghrita(PHBG), Polyherbal Bhallatakadi Murcchita Ghrita and Polyherbal Bhallatakadi Shata-Dhauta Ghrita formulations as per Ayurvedic procedures. The prepared ghrita formulations were subjected to organoleptic(colour, odour, taste, appearance and touch), physicochemical (pH, viscosity, moisture content, specificgravity, refractive index, acid value, saponification value, iodine value, peroxide value, Rechert Meisslvalue and Polenske value) evaluation, in-vitro antioxidant and GC-MS analysis. The accelerated and realtime stability studies were carried out to determine shelf life of ghrita formulations.Results: The results of evaluations indicate that, developed PHBG formulations retained the organolepticand physicochemical characteristics of ghee. The shelf life of formulations was found to be in the range of1.6 to 3.3 years at accelerated and 2.2 to 3.8 years at real time stability conditions. All ghrita formulationsexhibited antioxidant activity in dose dependent manner.Conclusion: The standardization or evaluation of Polyherbal Bhallatakadi Ghrita formulations was foundto be crucial for the establishment of a steady biological, chemical or simply a quality assurance profile ofthe drugsen_US
dc.identifier.affiliationsCenter for Research and Development, PRIST University, Thanjavur, Tamilnadu, Indiaen_US
dc.identifier.affiliationsGoa College of Pharmacy, Panaji, Goa, Indiaen_US
dc.identifier.citationWayal Sandesh R., Shailendra S. Gurav. Bhallatakadi Ghrita: Development and evaluation with reference to Murcchana and Shata-Dhauta process. Journal of Ayurveda and Integrative Medicine. 44013; 11(3): 261-269en_US
dc.identifier.issn0975-9476
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/214031
dc.languageenen_US
dc.publisherElsevieren_US
dc.relation.issuenumber3en_US
dc.relation.volume11en_US
dc.source.urihttps://dx.doi.org//10.1016/j.jaim.2020.05.005en_US
dc.subjectPolyherbalen_US
dc.subjectBhallatakadien_US
dc.subjectGhritaen_US
dc.subjectShata-Dhautaen_US
dc.subjectMurcchanaen_US
dc.titleBhallatakadi Ghrita: Development and evaluation with reference to Murcchana and Shata-Dhauta processen_US
dc.typeJournal Articleen_US
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