Antimicrobial susceptibility of Helicobacter pylori isolated from gastric biopsies in dyspeptic patients.

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dc.contributor.authorKulsuntiwong, Panthongen_US
dc.contributor.authorChomvarin, Chariyaen_US
dc.contributor.authorChaicumpar, Kunyaluken_US
dc.contributor.authorNamwat, Wisesen_US
dc.contributor.authorKaewkes, Wanlopen_US
dc.contributor.authorMairiang, Pisalnen_US
dc.contributor.authorSangchan, Apichaten_US
dc.date.accessioned2009-05-27T14:49:42Z
dc.date.available2009-05-27T14:49:42Z
dc.date.issued2008-11-10en_US
dc.descriptionThe Southeast Asian Journal of Tropical Medicine and Public Health.en_US
dc.description.abstractThe objective of this study was to evaluate the prevalence of antimicrobial resistance in Helicobacter pylori isolated from the antrum and corpus of dyspeptic patients in Khon Kaen, Thailand, and to compare the antimicrobial susceptibility patterns of H. pylori isolated from the antrum and corpus in individual patients. Antimicrobial susceptibility was determined by disk diffusion, studying susceptibility to metronidazole, clarithromycin, amoxicillin, erythromycin, ciprofloxacin, and tetracycline. The H. pylori resistant rate to at least one of the six antimicrobial agents tested was 37%. The resistance rates were 30.2% for metronidazole, 9.2% for ciprofloxacin, 5% for clarithromycin, 2.4% for amoxicillin, and 1.7% for erythromycin and tetracycline. Single, double, and more than double antimicrobial resistances were found in 27.7, 6.7 and 2.5%, respectively. Antimicrobial susceptibility testing revealed 11 antibiotypes. The most common antimicrobial susceptibility pattern found was sensitivity to 6 antimicrobial agents (63%). H. pylori antimicrobial resistance in specimens isolated from the antrum and corpus were nearly equivalent, 37.3% (22/59) and 36.7% (22/60), respectively. Most of the H. pylori specimens isolated from the antrum and corpus in individual patients were identical (87.7%).en_US
dc.description.affiliationDepartment of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.en_US
dc.identifier.citationKulsuntiwong P, Chomvarin C, Chaicumpar K, Namwat W, Kaewkes W, Mairiang P, Sangchan A. Antimicrobial susceptibility of Helicobacter pylori isolated from gastric biopsies in dyspeptic patients. The Southeast Asian Journal of Tropical Medicine and Public Health. 2008 Nov; 39(6): 1102-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/31193
dc.language.isoengen_US
dc.source.urihttps://www.tm.mahidol.ac.th/seameo/2008-39-6-full/23-4337.pdfen_US
dc.subject.meshAnti-Bacterial Agents --pharmacologyen_US
dc.subject.meshDisk Diffusion Antimicrobial Testsen_US
dc.subject.meshDrug Resistance, Bacterialen_US
dc.subject.meshDrug Resistance, Multiple, Bacterialen_US
dc.subject.meshDyspepsia --microbiologyen_US
dc.subject.meshHelicobacter pylori --drug effectsen_US
dc.subject.meshHumansen_US
dc.subject.meshPyloric Antrum --microbiologyen_US
dc.subject.meshThailand --epidemiologyen_US
dc.titleAntimicrobial susceptibility of Helicobacter pylori isolated from gastric biopsies in dyspeptic patients.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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