The effects of hematocrit and age on transcranial Doppler measurements in patients with recent ischemic stroke.

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dc.contributor.authorIsikay, Canan Togayen_US
dc.contributor.authorUzuner, Nevzaten_US
dc.contributor.authorGücüyener, Demeten_US
dc.contributor.authorOzdemir, Gazien_US
dc.date.accessioned2005-03-05en_US
dc.date.accessioned2009-06-03T10:47:04Z
dc.date.available2005-03-05en_US
dc.date.available2009-06-03T10:47:04Z
dc.date.issued2005-03-05en_US
dc.description.abstractBACKGROUND: The effects of age and hematocrit on transcranial Doppler (TCD) velocities have not been evaluated in a large patient group with recent ischemic stroke. AIM: This study assessed the effects of age and hematocrit on TCD measurements in patients with recent ischemic stroke compared to patients with non-vascular diseases. SETTINGS AND DESIGN: University Hospital, retrospective study. MATERIALS AND METHODS: TCD records and data files of 862 consecutive patients (mean age, 57+/-16 years) with various neurological diagnoses were reviewed retrospectively. The peak systolic, end diastolic and mean flow velocities (FV), systolic/diastolic ratios and pulsatility indices (PI) in the middle cerebral arteries were averaged and the effect of age and hematocrit values on these TCD values was studied. Independent samples t test, Pearson's coefficients of correlation, and linear regression test were used for statistical analysis. RESULTS: Among 862 patients, 413 were women (mean age, 53+/-17 years) and 449 were men (mean age, 60+/-13 years). Peak systolic and mean FV were higher and hematocrit concentration was lower in women compared to men (P< 0.001). The relation of TCD velocities with age and hematocrit was more remarkable in the group of patients with non-vascular neurological disorders. PI values demonstrated a significant correlation to age (r=+0.47) (P< 0.001), but did not change significantly with hematocrit level. CONCLUSIONS: It should be remembered that blood FV measured by TCD may be significantly affected by age and hematocrit level. However, there seems to be no significant association between TCD velocities and hematocrit in patients with a recent ischemic stroke.en_US
dc.description.affiliationDepartment of Neurology, Ankara University School of Medicine, Ibni Sina Hastanesi 6, 06100 Ankara, Turkey. isikay2@hotmail.comen_US
dc.identifier.citationIsikay CT, Uzuner N, Gücüyener D, Ozdemir G. The effects of hematocrit and age on transcranial Doppler measurements in patients with recent ischemic stroke. Neurology India. 2005 Mar; 53(1): 51-4; discussion 54en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/120453
dc.language.isoengen_US
dc.source.urihttps://neurologyindia.comen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAge Factorsen_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 and overen_US
dc.subject.meshBrain Ischemia --blooden_US
dc.subject.meshFemaleen_US
dc.subject.meshHematocriten_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshStroke --blooden_US
dc.subject.meshUltrasonography, Doppler, Transcranialen_US
dc.titleThe effects of hematocrit and age on transcranial Doppler measurements in patients with recent ischemic stroke.en_US
dc.typeJournal Articleen_US
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