Relation between central aortic pulse pressure and coronary artery disease: a coronary angiographic study in a tertiary care center

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dc.contributor.authorSubramanyam, K.en_US
dc.contributor.authorSuranagi, Manohar J.en_US
dc.contributor.authorSubramani, K. S.en_US
dc.contributor.authorRangaraj, R.en_US
dc.date.accessioned2020-04-09T07:43:28Z
dc.date.available2020-04-09T07:43:28Z
dc.date.issued2020-02
dc.description.abstractBackground: Aortic pulse pressure is a significant marker of cardiovascular morbidity independently of mean blood pressure and pulse pressure of 60 mm Hg should be considered as the threshold at risk both in normotensives and hypertensives. Coronary perfusion is dependent on diastolic blood pressure and patients with CAD may be susceptible to the adverse effects of low diastolic blood pressure. This study conducted to examine the relation between central aortic pulse pressure and the prevalence and extent of CAD.Methods: A cross sectional, hospital-based study conducted in Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bengaluru, among patients undergoing diagnostic coronary angiography.Results: Risk factors like Diabetes, Hypertension, Dyslipidemia and smoking rates were significantly higher in patients with PP of >60 mmHg (p<0.01). In the first group, the ratio of having normal coronaries is higher 61.9% vs 38% and diseased coronaries was lower when compared to the other group 38% vs 98%. In patients with aortic pulse pressure >60 mmHg, 4 patients had left main coronary artery (LMCA) disease, 20 patients had single vessel disease, 11 patients had two vessel disease and 20 patients had triple vessel disease.Conclusions: In this study it was demonstrated aortic pulse pressure of more than 60 mm Hg is associated with significant CAD.en_US
dc.identifier.affiliationsDepartment of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bengaluru, Karnataka, Indiaen_US
dc.identifier.citationSubramanyam K., Suranagi Manohar J., Subramani K. S., Rangaraj R.. Relation between central aortic pulse pressure and coronary artery disease: a coronary angiographic study in a tertiary care center. International Journal of Advances in Medicine. 2020 Feb; 7(2): 250-254en_US
dc.identifier.issn2349-3925
dc.identifier.issn2349-3933
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/194575
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber2en_US
dc.relation.volume7en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-3933.ijam20200074en_US
dc.subjectAortic pulse pressureen_US
dc.subjectCoronary artery diseaseen_US
dc.subjectCoronary perfusionen_US
dc.subjectHypertensionen_US
dc.titleRelation between central aortic pulse pressure and coronary artery disease: a coronary angiographic study in a tertiary care centeren_US
dc.typeJournal Articleen_US
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