Clinical decision making: managing postprandial hyperglycemia.

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dc.contributor.authorHurel, S Jen_US
dc.contributor.authorMohan, Ven_US
dc.date.accessioned2006-11-26en_US
dc.date.accessioned2009-05-31T03:24:58Z
dc.date.available2006-11-26en_US
dc.date.available2009-05-31T03:24:58Z
dc.date.issued2006-11-26en_US
dc.description44 references.en_US
dc.description.abstractThe primary objective of treating all patients with diabetes is to establish and maintain near-normal blood glucose levels to prevent microvascular and macrovascular complications. The glycated hemoglobin (HbA(1c)) is the accepted standard for monitoring overall glycemic control with treatments and management strategies traditionally targeting fasting and preprandial glucose levels. However, postprandial glucose levels also contribute to HbA(1c), and optimization of glycemic control may also require targeting these values. Exaggerated postmeal glucose excursions are common in patients with diabetes, and postprandial hyperglycemia (PPHG) is an independent risk factor for cardiovascular disease. Regular self-monitoring of blood glucose concentrations (SMBG) at appropriate times can detect PPHG, provide patient feedback regarding meals and lifestyle, and monitor response to therapy. SMBG can also help detect fluctuations in blood glucose levels, which may be an additional risk factor for complications, independent of HbA(1c). New therapeutic options that specifically target postprandial glucose levels may improve overall glycemic control and reduce the risk of microvascular and macrovascular complications.en_US
dc.description.affiliationUniversity College London Hospital, Department of Endocrinology and Diabetes, London, United Kingdom.en_US
dc.identifier.citationHurel SJ, Mohan V. Clinical decision making: managing postprandial hyperglycemia. Journal of the Association of Physicians of India. 2006 Nov; 54(): 871-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/93882
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshBlood Glucose --metabolismen_US
dc.subject.meshBlood Glucose Self-Monitoringen_US
dc.subject.meshCardiovascular Diseases --prevention & controlen_US
dc.subject.meshDiabetes Mellitus --blooden_US
dc.subject.meshHumansen_US
dc.subject.meshHyperglycemia --therapyen_US
dc.subject.meshPostprandial Perioden_US
dc.subject.meshRisk Factorsen_US
dc.titleClinical decision making: managing postprandial hyperglycemia.en_US
dc.typeJournal Articleen_US
dc.typeReviewen_US
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