Brainstem auditory evoked response in newborns with hyperbilirubinemia.

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dc.contributor.authorAgrawal, V Ken_US
dc.contributor.authorShukla, Ren_US
dc.contributor.authorMisra, P Ken_US
dc.contributor.authorKapoor, R Ken_US
dc.contributor.authorMalik, G Ken_US
dc.date.accessioned1998-06-27en_US
dc.date.accessioned2009-05-27T05:27:49Z
dc.date.available1998-06-27en_US
dc.date.available2009-05-27T05:27:49Z
dc.date.issued1998-06-27en_US
dc.description.abstractOBJECTIVE: To determine the initial Brainstem Auditory Evoked Response (BAER) abnormalities in neonates with hyperbilirubinemia and the possible reversibility of abnormal BAER after therapy. DESIGN: Prospective cohort study. SETTING: Tertiary care hospital. SUBJECTS: 30 term neonates with hyperbilirubinemia (S. bilirubin < 15 mg/dl) as cases and 25 normal term neonates as controls. METHODS: Duration of study was from August 1995 to August 1996. BAER were recorded before therapy at peak hyperbilirubinemia, after therapy, and the age of 2-4 months using electric response audiometer (Nihon Neuropack Four Machine). Denver Development Screening Test (Denver II) was performed at 1 year of age. RESULTS: Seventeen out of thirty (56.7%) neonates with hyperbilirubinemia showed abnormalities on initial BAER. Commonest abnormality seen was raised threshold of wave V in 12 neonates (40%). Other abnormalities observed were absence of all waves at 90 dB (23.3%), prolongation of latencies of various waves (26.7%) and prolongation of various intervals (26.7%). Abnormalities in BAER correlated significantly with bilirubin level. After therapy abnormalities reverted back to normal in 10 cases but persisted in 7 out of 17 (41.17%) cases with initial abnormal BAER. Development screening at 1 yr was abnormal in 3 infants all of whom had persistent abnormalities in BAER. CONCLUSION: Serial BAER is a useful, non invasive tool to detect neurodevelopment delay secondary to neonatal hyperbilirubinemia.en_US
dc.description.affiliationDepartment of Pediatrics, King George's Medical College, Lucknow.en_US
dc.identifier.citationAgrawal VK, Shukla R, Misra PK, Kapoor RK, Malik GK. Brainstem auditory evoked response in newborns with hyperbilirubinemia. Indian Pediatrics. 1998 Jun; 35(6): 513-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/11031
dc.language.isoengen_US
dc.source.urihttps://indianpediatrics.neten_US
dc.subject.meshAuditory Thresholden_US
dc.subject.meshBilirubin --blooden_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshEvoked Potentials, Auditory, Brain Stemen_US
dc.subject.meshFemaleen_US
dc.subject.meshHearing Loss, Sensorineural --etiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshInfanten_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshJaundice, Neonatal --blooden_US
dc.subject.meshMaleen_US
dc.subject.meshMass Screeningen_US
dc.subject.meshProspective Studiesen_US
dc.titleBrainstem auditory evoked response in newborns with hyperbilirubinemia.en_US
dc.typeJournal Articleen_US
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