Synergistic Occurrence of EGFR, ALK, and KRAS Gene Mutations in a Patient with Non-small Cell Lung Cancer (Adenocarcinoma)
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Date
2019-01
Journal Title
Journal ISSN
Volume Title
Publisher
Scientific Scholar
Abstract
Lung cancer is a commonly diagnosed malignancy. Adenocarcinoma, a subgroup of non-small cell lung cancer, is the commonest form and presents in an advanced stage of the disease, leaving a limited treatment option. Response to the standard chemotherapy regimens is overall poor. We present a case of synergistic occurrence of triple gene mutations in a patient with well-diff erentiated adenocarcinoma lung treated at a tertiary cancer care center in North India.
Description
Keywords
Non-small cell lung cancer, EGFR, ALK, KRAS
Citation
Doval Dinesh Chandra, Tripathi Rupal, Choudhury Kumardeep Dutta, Sharma Ajay, Batra Ullas, Mehta Anurag, Choudhury PS. Synergistic Occurrence of EGFR, ALK, and KRAS Gene Mutations in a Patient with Non-small Cell Lung Cancer (Adenocarcinoma). Indian Journal of Medical Sciences. 2019 Jan; 71(1): 45-48