Scientific Opinion on the Regulatory Status of 1,3-Dimethylamylamine (DMAA).
Loading...
Date
2012-10
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
1,3-Dimethylamylamine (DMAA) is a pressor amine often found in food supplements for
athletes at dosages of 25-65 mg. Historically, the compound has been used as a nasal
decongestant but its oral application is largely unstudied leaving the regulatory status of
such food supplements as unlicensed medicines undetermined. We therefore reviewed
the literature on DMAA and similar amines in order to deduce an effective oral dosage.
Based on our findings we conclude that oral preparations with >4 mg DMAA per dose unit
should be considered as effective as a bronchodilator. Food supplements that exceed that
limit are in fact subject to the Medicines Act and require licensing. Dosages higher than
100-200 mg are expected to cause serious adverse events.
Description
Keywords
1,3-Dimethylamylamine (DMAA), geranamine, regulatory status, food supplements, oral efficacy
Citation
Venhuis Bastiaan J, Kaste Dries de. Scientific Opinion on the Regulatory Status of 1,3-Dimethylamylamine (DMAA). European Journal of Nutrition & Food Safety. 2012 Oct-Dec; 2(4): 93-100.