Protective effect of curcumin during selenium induced toxicity on dehydrogenases in hepatic tissue.

Simple item page
dc.contributor.authorPadmaja, Sen_US
dc.contributor.authorRaju, T Nen_US
dc.date.accessioned2005-01-11en_US
dc.date.accessioned2009-06-01T06:18:26Z
dc.date.available2005-01-11en_US
dc.date.available2009-06-01T06:18:26Z
dc.date.issued2005-01-11en_US
dc.description.abstractSelenium administration resulted in a marked decrease in the activity levels of the liver succinate dehydrogenase, malate dehydrogenase, and lactate dehydrogenase while pyruvate dehydrogenase increased significantly (P<0.001) in the wistar rat. The degree of decrease of these enzymes was significantly less (P<0.001) when rats were treated with curcumin, a natural constituent Curcuma longa. Curcumin seems to prevent oxidative damage mediated through selenium and protect the dehydrogenases possibly through its anti-oxidative property.en_US
dc.description.affiliationPhysiology Division, Department of Zoology, University College of Science, Osmania University, Hyderabad - 500 007.en_US
dc.identifier.citationPadmaja S, Raju TN. Protective effect of curcumin during selenium induced toxicity on dehydrogenases in hepatic tissue. Indian Journal of Physiology and Pharmacology. 2005 Jan; 49(1): 111-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/107285
dc.language.isoengen_US
dc.source.urihttps://www.ijpp.comen_US
dc.subject.meshAdministration, Oralen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntioxidants --administration & dosageen_US
dc.subject.meshCurcumin --administration & dosageen_US
dc.subject.meshEnzyme Inhibitors --administration & dosageen_US
dc.subject.meshL-Lactate Dehydrogenase --antagonists & inhibitorsen_US
dc.subject.meshLiver --drug effectsen_US
dc.subject.meshMalate Dehydrogenase --antagonists & inhibitorsen_US
dc.subject.meshMaleen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Wistaren_US
dc.subject.meshSelenium --toxicityen_US
dc.subject.meshSuccinate Dehydrogenase --antagonists & inhibitorsen_US
dc.titleProtective effect of curcumin during selenium induced toxicity on dehydrogenases in hepatic tissue.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Physiology and Pharmacology