Evaluation of Mannose Binding Lectin Levels in Hypertensive Patients of Tertiary Care Teaching Hospital in Central India

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dc.contributor.authorKhare, Ruchien_US
dc.contributor.authorNigoskar, Shreyaen_US
dc.date.accessioned2024-09-24T08:08:41Z
dc.date.available2024-09-24T08:08:41Z
dc.date.issued2023-04
dc.description.abstractBackground: The present study was conducted for evaluating Mannose Binding Lectin levels in hypertensive patients. Materials & Methods: The study included 100 hypertension cases and 100 controls who met the inclusion requirements. All subjects had 5 mL of blood drawn into serum tubes after an overnight fast. After letting the blood clot for 15 minutes at 3000 RPM, the serum was centrifuged out. For the mannose binding lectin test, 0.5 mL of serum had to be stored at - 20°C. ELISA technique was used for evaluating the serum mannose binding lectin levels. All the results were recorded on a Microsoft excel sheet followed by statistical analysis using SPSS software. Results: The mean Mannose Binding Lectin (MBL) in Cases was more (912.56 ± 43.51) as compared to Controls (612.18 ± 21.43) shows statistically significant. (By Un-paired T test; p>0.05). The above table shows the association of type (NYHA) of hypertension and MBL among cases. The mean MBL in Stage II was more (968.39 ± 46.41) as compared to Stage I (856.13 ± 40.56) shows statistically significant. (By Un- paired T test; p>0.05) Conclusion: The present study concludes that, high MBL levels are associated with an increased risk of coronary artery disease and are high in the serum prior to the development of hypertensive symptoms.en_US
dc.identifier.affiliationsResearch Scholar, Malwanchal University, Indore, Madhya Pradesh, Indiaen_US
dc.identifier.affiliationsResearch Supervisor, Professor and Head, Department of Biochemistry, Index Medical College, Hospital and Research Centre, Indore, Madhya Pradesh, Indiaen_US
dc.identifier.citationKhare Ruchi, Nigoskar Shreya. Evaluation of Mannose Binding Lectin Levels in Hypertensive Patients of Tertiary Care Teaching Hospital in Central India. International Journal of Medical Research Professionals. 2023 Mar; 9(2): 13-15en_US
dc.identifier.issn2454-6356
dc.identifier.issn2454-6364
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/231032
dc.languageenen_US
dc.publisherIbn Sina Academy of Medieval Medicine & Sciencesen_US
dc.relation.issuenumber2en_US
dc.relation.volume9en_US
dc.source.urihttps://doi.org/10.21276/ijmrp.2023.9.2.003en_US
dc.subjectMannose Binding lectinen_US
dc.subjectHypertensionen_US
dc.titleEvaluation of Mannose Binding Lectin Levels in Hypertensive Patients of Tertiary Care Teaching Hospital in Central Indiaen_US
dc.typeJournal Articleen_US
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