Malignant ovarian germ cell tumor in King Chulalongkorn Memorial Hospital.

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dc.contributor.authorLertkhachonsuk, Ruangsaken_US
dc.contributor.authorTermrungruanglert, Wichaien_US
dc.contributor.authorVasuratna, Apichaien_US
dc.contributor.authorSittisomwong, Tulen_US
dc.contributor.authorWorasethsin, Pongkasemen_US
dc.contributor.authorTresukosol, Damrongen_US
dc.date.accessioned2009-05-27T20:18:33Z
dc.date.available2009-05-27T20:18:33Z
dc.date.issued2005-09-21en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractOBJECTIVES: To determine the frequency, characteristics, treatment and outcome of patients with malignant ovarian germ cell tumor (MOGCT) in King Chulalongkorn Memorial Hospital during the period January 1992 - December 2000. STUDY DESIGN: Retrospective descriptive study MATERIAL AND METHOD: All patients with malignant ovarian germ cell tumor in King Chulalongkorn Memorial Hospital during the period January 1992 - December 2000 were analyzed by the characteristics of patients, treatment and outcome. RESULTS: Sixty-six patients with MOGCT were demonstrated in that period with a mean age of 22.6 years old. Most of the patients were nulliparous and premenopausal status. Primary surgery was done in all patients. Forty-two patients (63.6%) received conservative surgery. Eight patients received no adjuvant treatment after surgery due to stage 1A dysgerminoma and immature teratoma stage I grade I. Fifty-six patients received chemotherapy for adjuvant treatment. VAC regimen was given in 27 cases (40.9%) and PVB regimen was given in 25 cases (37.9%). Salvage therapy in the patients with persistent and recurrent disease was treated in 9 patients, who received a platinum-base of regimen. Two-year survival was 88% with the median time to follow up 24 months. Overall five-year survival in the present study was 85%. CONCLUSION: MOGCT in King Chulalongkorn Memorial Hospital had clinical characteristics similar to other studies in malignant ovarian germ cell tumor Treatment by VAC regimen still has benefit in selected group.en_US
dc.description.affiliationGynecologic Oncology Unit, Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.en_US
dc.identifier.citationLertkhachonsuk R, Termrungruanglert W, Vasuratna A, Sittisomwong T, Worasethsin P, Tresukosol D. Malignant ovarian germ cell tumor in King Chulalongkorn Memorial Hospital. Journal of the Medical Association of Thailand. 2005 Sep; 88 Suppl 4(): S124-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/42758
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshChemotherapy, Adjuvanten_US
dc.subject.meshChilden_US
dc.subject.meshFemaleen_US
dc.subject.meshHospitalization --statistics & numerical dataen_US
dc.subject.meshHospitals, Urban --utilizationen_US
dc.subject.meshHumansen_US
dc.subject.meshIncidenceen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeoplasms, Germ Cell and Embryonal --epidemiologyen_US
dc.subject.meshOvarian Neoplasms --epidemiologyen_US
dc.subject.meshRadiotherapy, Adjuvanten_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshSalvage Therapyen_US
dc.subject.meshSurvival Analysisen_US
dc.subject.meshThailand --epidemiologyen_US
dc.subject.meshTreatment Outcomeen_US
dc.titleMalignant ovarian germ cell tumor in King Chulalongkorn Memorial Hospital.en_US
dc.typeJournal Articleen_US
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