Nature of leukemia-associated antigenicity of dinitrophenylated human lymphocytes and lymphoblasts.
Loading...
Date
1981-03
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Using dinitrophenylated human lymphocytes and phytohaemagglutinin–stimulated
human lymphoblasts as antigens, antibodies were produced in rabbits. The immunological
reactivities of the antisera so produced were tested against various types of leukemic cells after
absorbing the sera with pooled normal leukocytes. Both the sera showed reactivity with all
types of leukemic cells and no specific affinity for lymphoid leukemic cells was seen. This may
suggest the presence of some common antigens on all types of leukemic cells or that
dinitrophenylation brings about similar changes on all types of normal leukocytes.
Description
Keywords
Dinitrophenylation, lymphocytes, lymphoblasts, leukoagglutination, immunoprecipitation, immunofluorescence, leukemia–associated antigens
Citation
Joshi S S, Basrur V S, Sahasrabudhe M B. Nature of leukemia-associated antigenicity of dinitrophenylated human lymphocytes and lymphoblasts. Journal of Biosciences. 1981 Mar; 3(1): 69-76.