Epithelioid trophoblastic tumor of uterus presenting as an ovarian mass: a diagnostic and therapeutic dilemma.

Simple item page
dc.contributor.authorShet, Tanujaen_US
dc.contributor.authorParage, Mahendraen_US
dc.contributor.authorMaheshwari, Amitaen_US
dc.contributor.authorNair, Reenaen_US
dc.contributor.authorGupta, Sudeepen_US
dc.contributor.authorTongaonkar, Hemanten_US
dc.contributor.authorChinoy, Roshanen_US
dc.date.accessioned2008-04-08en_US
dc.date.accessioned2009-05-29T11:50:56Z
dc.date.available2008-04-08en_US
dc.date.available2009-05-29T11:50:56Z
dc.date.issued2008-04-08en_US
dc.description.abstractEpithelioid trophoblastic tumor (ETT) is a rare gestational trophoblastic tumor and often poses a diagnostic and therapeutic challenge to the involved clinicians. We report a case of epithelioid trophoblastic tumor in a young woman which involved the uterus, parametrium and the right ovary. Misdiagnosis as a choriocarcinoma led to improper treatment and progressive disease. Microscopically it revealed a relatively monotonous population of epithelioid cells arranged in nests with hyaline-like matrix surrounding the tumor cells. Differential diagnosis between placental site trophoblastic tumor and carcinoma was ruled out based on histology and immunohistochemistry. The patient developed lung and brain metastasis after 10 months and is alive with disease 1(1/2) years thereafter and is taking palliative chemotherapy. The patient had beta-HCG level of 85.1 mIU/mL at the time of diagnosis; but just before metastasis, the levels rose. Awareness of the histological features of ETT is essential to avoid misdiagnosis, as it represents a tumor which is primarily treated by surgery rather than with chemotherapy.en_US
dc.description.affiliationDepartment of Pathology, Tata Memorial Hospital, Parel, Mumbai, India. tanujashet@yahoo.comen_US
dc.identifier.citationShet T, Parage M, Maheshwari A, Nair R, Gupta S, Tongaonkar H, Chinoy R. Epithelioid trophoblastic tumor of uterus presenting as an ovarian mass: a diagnostic and therapeutic dilemma. Indian Journal of Pathology & Microbiology. 2008 Apr-Jun; 51(2): 242-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/73959
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAdulten_US
dc.subject.meshChoriocarcinoma --diagnosisen_US
dc.subject.meshChorionic Gonadotropin --blooden_US
dc.subject.meshDiagnosis, Differentialen_US
dc.subject.meshFemaleen_US
dc.subject.meshGestational Trophoblastic Neoplasms --blooden_US
dc.subject.meshHumansen_US
dc.subject.meshOvarian Neoplasms --diagnosisen_US
dc.subject.meshPregnancyen_US
dc.subject.meshUterine Neoplasms --blooden_US
dc.titleEpithelioid trophoblastic tumor of uterus presenting as an ovarian mass: a diagnostic and therapeutic dilemma.en_US
dc.typeCase Reportsen_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Pathology & Microbiology