Comparison of effects of olanzapine and risperidone on body mass index and blood sugar level in schizophrenic patients.
| dc.contributor.author | Ingole, Shahu | |
| dc.contributor.author | Belorkar, N R | |
| dc.contributor.author | Waradkar, Praveer | |
| dc.contributor.author | Shrivastava, Meena | |
| dc.date.accessioned | 2013-04-03T10:14:47Z | |
| dc.date.available | 2013-04-03T10:14:47Z | |
| dc.date.issued | 2009-01 | |
| dc.description.abstract | Schizophrenia is one of the most debilitating disorders with devastating effects on its victims and their families. Atypical antipsychotics (AAPs) because of their superior efficacy, reduced side effects, & better compliance, have rapidly become the mainstay of treatment. But, because of paucity of research & literature on the long-term metabolic side effect profile of these AAPs in Indian setup, this prospective study has been carried out to compare the effects of olanzapine & risperidone on body weight, body mass index, & blood sugar level in schizophrenic patients. Among 60 newly diagnosed DSM-IV patients of schizophrenia enrolled, it was observed that mean body weight & BMI were significantly increased from baseline to 6 & 12 weeks in both olanzapine (n=30) & risperidone groups (n=30) (P<0.001). Also, mean blood sugar was found to be significantly elevated after 6 & 12 weeks of treatment with olanzapine (P<0.001) but not in risperidone group. Thus, the present study underscores the need for baseline and six weekly monitoring of body weight and blood glucose in routine clinical practice with AAPs. | en_US |
| dc.identifier.citation | Ingole Shahu, Belorkar N R, Waradkar Praveer, Shrivastava Meena. Comparison of effects of olanzapine and risperidone on body mass index and blood sugar level in schizophrenic patients. Indian Journal of Physiology and Pharmacology. 2009 Jan-Mar; 53(1): 47-54. | en_US |
| dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/145904 | |
| dc.language.iso | en | en_US |
| dc.source.uri | https://www.ijpp.com/IJPP%20archives/2009_53_1_Jan%20-%20Mar/47-54.pdf | en_US |
| dc.subject | Schizophrenia | en_US |
| dc.subject | olanzapine | en_US |
| dc.subject | risperidone | en_US |
| dc.subject | body mass index | en_US |
| dc.subject | blood sugar | en_US |
| dc.title | Comparison of effects of olanzapine and risperidone on body mass index and blood sugar level in schizophrenic patients. | en_US |
| dc.type | Article | en_US |