Seroepidemiology of hepatitis A in Delhi.

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dc.contributor.authorDutta, A Ken_US
dc.contributor.authorAggarwal, Aen_US
dc.contributor.authorKapoor, A Ken_US
dc.contributor.authorRay, G Nen_US
dc.contributor.authorBatra, Sen_US
dc.date.accessioned2000-02-01en_US
dc.date.accessioned2009-05-30T10:47:57Z
dc.date.available2000-02-01en_US
dc.date.available2009-05-30T10:47:57Z
dc.date.issued2000-02-01en_US
dc.description.abstractA prospective study was done to determine the age specific prevalence of antihepatitis A antibodies (anti HAV Abs) among children in Delhi. Four hundred and twenty children aged 0-12 years attending outpatient department for vaccination or any minor illness were studied. Sera was tested by ELISA for anti HAV Abs using a commercial kit (Hepvase A 96 TMB). Thirty samples of cord blood were similarly analyzed. All samples of cord blood were positive for anti HAV Abs. Prevalence of anti HAV Abs was 80% by 5 years of age. The most vulnerable age group was 0.5-1.5 years (anti HAV Ab positivity). Cord blood had 100% positivity. Univariate and multivariate analyses taking anti HAV antibody positivity as dependant variable demonstrated that age and father's education (socioeconomic status) significantly affect prevalence of anti HAV Abs. Sex, water supply, history of jaundice in self or family did not have any significant effect on anti HAV antibody positivity. Prevalence of anti HAV antibodies is 80% by 5 years of age. Further studies in different strata of society and different regions in the country are required to assess the need and age for vaccination.en_US
dc.description.affiliationDepartment of Pediatrics, Kalawati Saran Children's Hospital, Lady Hardinge Medical College, New Delhi.en_US
dc.identifier.citationDutta AK, Aggarwal A, Kapoor AK, Ray GN, Batra S. Seroepidemiology of hepatitis A in Delhi. Indian Journal of Pediatrics. 2000 Feb; 67(2): 77-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/79018
dc.language.isoengen_US
dc.source.urihttps://medind.nic.in/icb/icbai.shtmlen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshFemaleen_US
dc.subject.meshHepatitis A --epidemiologyen_US
dc.subject.meshHepatitis C Antibodies --analysisen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshInfanten_US
dc.subject.meshMaleen_US
dc.subject.meshPrevalenceen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshSeroepidemiologic Studiesen_US
dc.titleSeroepidemiology of hepatitis A in Delhi.en_US
dc.typeJournal Articleen_US
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