Lipoblastoma of the lip

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dc.contributor.authorCota, Jen_US
dc.contributor.authorBorkar, RRen_US
dc.contributor.authorSavalkar, JJen_US
dc.contributor.authorChalakkal, Pen_US
dc.contributor.authorSpadigam, Aen_US
dc.date.accessioned2025-06-19T05:55:12Z
dc.date.available2025-06-19T05:55:12Z
dc.date.issued2025-03
dc.description.abstractLipoblastomas are benign tumors arising from embryonic white fatty cells that continue to proliferate and develop during the postnatal period. It commonly affects children 3 years of age or younger, with the neck being the most frequent site in the head and neck region. Only 10% of cases are seen at 10 years or above. The etiopathogenesis of lipoblastomas is linked to polysomy and rearrangement of chromosome 8q11–13 with or without the involvement of the pleomorphic adenoma gene 1 (PLAG1) gene. Here, we report one of the first cases of lipoblastoma of lip in a 10?year?old boy with atypical immunohistochemical features and the need for thorough clinical and histopathological evaluation of cases with atypical findings. The novel pathogenetic mechanism of lipoblastoma from the cluster of differentiation 34?positive (CD34+) stem cells has also been discussed.en_US
dc.identifier.affiliationsDepartments of Oral and Maxillofacial Pathologyen_US
dc.identifier.affiliationsDepartments of Oral and Maxillofacial Pathologyen_US
dc.identifier.affiliationsPediatric and Preventive Dentistry, Goa Dental College and Hospital, Bambolim, Goa, Indiaen_US
dc.identifier.affiliationsDepartments of Oral and Maxillofacial Pathologyen_US
dc.identifier.affiliationsPediatric and Preventive Dentistry, Goa Dental College and Hospital, Bambolim, Goa, Indiaen_US
dc.identifier.affiliationsDepartments of Oral and Maxillofacial Pathologyen_US
dc.identifier.citationCota J, Borkar RR, Savalkar JJ, Chalakkal P, Spadigam A. Lipoblastoma of the lip. Indian Journal of Pathology & Microbiology. 2025 Mar; 68(1): 204-207en_US
dc.identifier.issn0377-4929
dc.identifier.issn0974-5130
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/249954
dc.languageenen_US
dc.publisherWolters Kluwer - Medknowen_US
dc.relation.issuenumber1en_US
dc.relation.volume68en_US
dc.source.urihttps://doi.org/10.4103/ijpm.ijpm_841_23en_US
dc.subjectLipen_US
dc.subjectlipoblastomaen_US
dc.subjectpediatricsen_US
dc.subjectPLAG1en_US
dc.titleLipoblastoma of the lipen_US
dc.typeJournal Articleen_US
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