Comparative efficacy of chloroquine and amodiaquine in Plasmodium falciparum strain of north-eastern India.

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dc.contributor.authorPandya, A Pen_US
dc.contributor.authorBarkakaty, B Nen_US
dc.contributor.authorNarasimham, M Ven_US
dc.date.accessioned1994-06-01en_US
dc.date.accessioned2009-06-01T19:15:56Z
dc.date.available1994-06-01en_US
dc.date.available2009-06-01T19:15:56Z
dc.date.issued1994-06-01en_US
dc.description.abstractThe present study describes the comparative efficacy of chloroquine and amodiaquine in two different presumptive therapy areas of north eastern India. The study recorded insignificant differences in respect of Mean Parasite Clearance Time (MPCT) of sensitive cases, MPCT and Mean Parasite Recrudescence Time (MPRT) of RI resistant cases and recrudescence rate in chloroquine and amodiaquine therapy areas. It is concluded that amodiaquine is not a superior drug as compared to chloroquine. In the chloroquine resistance area, Plasmodium falciparum developed cross resistance to amodiaquine and this phenomenon appears to be unidirectional. However, amodiaquine may help to slow-down the rate of precipitation of higher grade of resistance.en_US
dc.description.affiliationRegional Office for Health & Family Welfare, Industrial Estate Corner, Anand Estate Bapunagar, Ahmedabad.en_US
dc.identifier.citationPandya AP, Barkakaty BN, Narasimham MV. Comparative efficacy of chloroquine and amodiaquine in Plasmodium falciparum strain of north-eastern India. Journal of Communicable Diseases. 1994 Jun; 26(2): 61-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/112827
dc.language.isoengen_US
dc.subject.meshAmodiaquine --therapeutic useen_US
dc.subject.meshAnimalsen_US
dc.subject.meshChloroquine --therapeutic useen_US
dc.subject.meshDrug Resistanceen_US
dc.subject.meshHumansen_US
dc.subject.meshIndiaen_US
dc.subject.meshMalaria, Falciparum --drug therapyen_US
dc.subject.meshPlasmodium falciparum --drug effectsen_US
dc.subject.meshPrevalenceen_US
dc.subject.meshTime Factorsen_US
dc.titleComparative efficacy of chloroquine and amodiaquine in Plasmodium falciparum strain of north-eastern India.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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