Wheezing in Preschool Children and Total IgE Levels: A Birth Cohort Study

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dc.contributor.authorJat, Kana Ramen_US
dc.contributor.authorKumar, Prawinen_US
dc.contributor.authorMukherjee, Aparnaen_US
dc.contributor.authorShivani, Randeven_US
dc.contributor.authorBipin, Joseen_US
dc.contributor.authorM, Kalaivanien_US
dc.contributor.authorLodha, Rakeshen_US
dc.contributor.authorKabra, Sushil Ken_US
dc.date.accessioned2020-04-23T07:45:04Z
dc.date.available2020-04-23T07:45:04Z
dc.date.issued2020-03
dc.description.abstractObjectives: To evaluate association between total IgE levels and wheezing in preschoolchildren from India. Methods: Datawere collected in a prospective birth cohort study relatedto wheezing till three years of age. Total IgE was measured at enrolment, at one year and twoyears of age and correlated with wheezing episodes. Results: A total of310 (167 boys)children were enrolled. Total IgE levels increased with age (P<0.001). Overall, 101 (32.6%)children had 182 episodes of wheezing. The median (IQR) total IgE levels in children withwheezing and without wheezing were similar at one year [42.1 (12.7, 93.5) vs 41.9 (17.1,96.7) kU/L; P=0.39] and two years of age [62.8 (32.4, 212.0) vs 75 (25.8, 173.0) kU/L,P=0.92). Conclusion: Total IgE levels increased with age and were not different in preschoolchildren with and without wheezing.en_US
dc.identifier.affiliationsDepartments of Pediatrics, All India Institute of Medical Sciences, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartments of Pediatrics, All India Institute of Medical Sciences, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartments of Pediatrics, All India Institute of Medical Sciences, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartments of Pediatrics, All India Institute of Medical Sciences, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartments of Pediatrics, All India Institute of Medical Sciences, New Delhi, Indiaen_US
dc.identifier.affiliationsBiostatistics, All India Institute of Medical Sciences, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartments of Pediatrics, All India Institute of Medical Sciences, New Delhi, Indiaen_US
dc.identifier.affiliationsDepartments of Pediatrics, All India Institute of Medical Sciences, New Delhi, Indiaen_US
dc.identifier.citationJat Kana Ram, Kumar Prawin, Mukherjee Aparna, Shivani Randev, Bipin Jose, M Kalaivani, Lodha Rakesh, Kabra Sushil K. Wheezing in Preschool Children and Total IgE Levels: A Birth Cohort Study. Indian Pediatrics. 2020 Mar; 57(3): 235-238en_US
dc.identifier.issn0974-7559
dc.identifier.issn0019-6061
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/199504
dc.languageenen_US
dc.publisherIndian Academy of Pediatricsen_US
dc.relation.issuenumber3en_US
dc.relation.volume57en_US
dc.source.urihttps://www.indianpediatrics.net/mar2020/235.pdfen_US
dc.subjectImmunoglobin Een_US
dc.subjectRhonchien_US
dc.subjectUnder-five wheezeren_US
dc.titleWheezing in Preschool Children and Total IgE Levels: A Birth Cohort Studyen_US
dc.typeJournal Articleen_US
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