Utility of bronchoalveolar lavage in the diagnosis of pulmonary infections in immunosuppressed patients.

Simple item page
dc.contributor.authorMenon, L Ren_US
dc.contributor.authorDivate, Sen_US
dc.contributor.authorAcharya, V Nen_US
dc.contributor.authorMahashur, A Aen_US
dc.contributor.authorNatrajan, Gen_US
dc.contributor.authorAlmeida, A Fen_US
dc.date.accessioned2002-09-09en_US
dc.date.accessioned2009-05-30T22:59:09Z
dc.date.available2002-09-09en_US
dc.date.available2009-05-30T22:59:09Z
dc.date.issued2002-09-09en_US
dc.description.abstractAIM: To evaluate the utility of bronchoalveolar lavage (BAL) in immunocompromised patients. MATERIAL AND METHODS: We studied BAL cytology and microbiological culture in 16 kidney transplant recipients (Group A), 14 dialysis patients (Group B) and eight HIV positive patients (Group C) suspected of having pulmonary infections. A group of 21 individuals without pulmonary diseases were studied as controls. RESULTS: A comparison of the cytological profile in controls and study groups showed that percentages of lymphocytes and neutrophils were significantly increased in all three patient groups as compared to controls, BAL bacterial cultures were positive in 4, 3 and 4 cases of Group A, B and C, respectively. Direct examination of BAL cytosmears helped in detecting cytomegalovirus inclusions, acid fast bacilli and Pneumocystis carinii in 3, 2 and 5 cases of Group A, B and C, respectively though microbial cultures were negative. The sensitivity of BAL cytology was found to be 76.3%, whereas that of microbial culture was only 31.5%. The diagnostic yield of BAL was 68.75%, 71.42% and 100% in the Groups A, B and C, respectively, while it was 76% when all three groups were considered together. BAL cytology yielded the diagnosis in 47.36% of cases, a combination of BAL cytology and culture in 23.68% and culture alone in 5.3% of cases. CONCLUSIONS: BAL is useful relatively non-invasive investigative tool in the rapid diagnosis of infections in immunocompromised patients. BAL cytology was found to be more useful than microbial cultures.en_US
dc.description.affiliationDepartment of Pathology, KEM Hospital, Seth GS Medical College, Parel, Mumbai 400 012.en_US
dc.identifier.citationMenon LR, Divate S, Acharya VN, Mahashur AA, Natrajan G, Almeida AF. Utility of bronchoalveolar lavage in the diagnosis of pulmonary infections in immunosuppressed patients. Journal of the Association of Physicians of India. 2002 Sep; 50(): 1110-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/90019
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshBronchoalveolar Lavageen_US
dc.subject.meshBronchoalveolar Lavage Fluid --cytologyen_US
dc.subject.meshHIV Infections --immunologyen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunocompromised Host --immunologyen_US
dc.subject.meshKidney Failure --immunologyen_US
dc.subject.meshKidney Transplantation --immunologyen_US
dc.subject.meshRenal Dialysisen_US
dc.subject.meshRespiratory Tract Infections --immunologyen_US
dc.titleUtility of bronchoalveolar lavage in the diagnosis of pulmonary infections in immunosuppressed patients.en_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Journal of the Association of Physicians of India