Henoch-Schönlein purpura in Chinese children and adults.

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dc.contributor.authorLin, S Jen_US
dc.contributor.authorHuang, J Len_US
dc.date.accessioned2009-05-27T17:15:43Z
dc.date.available2009-05-27T17:15:43Z
dc.date.issued1998-03-29en_US
dc.descriptionPublished by the Allergy and Immunology Society of Thailand.en_US
dc.description.abstractFrom 1987 to 1996, we retrospectively analyzed 84 children and 38 adults admitted to Chang Gung Memorial Hospital with the diagnosis of Henoch-Schönlein purpura (HSP). All of the adult patients had skin biopsy finding showing leukocytoclastic vasculitis. Male predominance was noted in children, but not in adults. Preceding infection was noted in 40.5% of children and 31.6% of the adults (P = 0.46). 8.3% of children and 13.2% of adults had medication intake at disease onset (P = 0.62). Children had more frequent abdominal pain than the adults (70.2% vs 28.9%, P < 0.01). Renal involvement was more common and severe in adults, manifested as more frequent hypertension (P < 0.05) and heavy proteinuria (P < 0.01). During acute attack, leukocytosis, thrombocytosis, elevation of serum C-reactive protein levels were more frequently observed in children, while elevated serum IgA and cryoglobulin levels were more common in adults. The overall prognosis was good in both age groups, although two adults developed end stage renal disease. Our study demonstrated the different expression of HSP in Chinese children and adults.en_US
dc.description.affiliationDepartment of Pediatrics, Chang Gung Children's Hospital, Kweishan, Taoyuan, Taiwan.en_US
dc.identifier.citationLin SJ, Huang JL. Henoch-Schönlein purpura in Chinese children and adults. Asian Pacific Journal of Allergy and Immunology. 1998 Mar; 16(1): 21-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/36805
dc.language.isoengen_US
dc.subject.meshAdulten_US
dc.subject.meshBiopsyen_US
dc.subject.meshBlood Platelets --immunologyen_US
dc.subject.meshC-Reactive Protein --analysisen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshCryoglobulins --analysisen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunoglobulin A --blooden_US
dc.subject.meshLeukocyte Counten_US
dc.subject.meshLongitudinal Studiesen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPurpura, Schoenlein-Henoch --diagnosisen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshSkin --pathologyen_US
dc.subject.meshTaiwan --epidemiologyen_US
dc.titleHenoch-Schönlein purpura in Chinese children and adults.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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