Hypocalcemia in the Newborn.
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Date
2010-10
Journal Title
Journal ISSN
Volume Title
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Abstract
Hypocalcemia is a frequently observed clinical
and laboratory abnormality in neonates. Ionic calcium is
crucial for many biochemical processes including blood
coagulation, neuromuscular excitability, cell membrane
integrity, and many of the cellular enzymatic activities.
Healthy term infants undergo a physiological nadir in
serum calcium levels by 24-48 h of age. This nadir may
drop to hypocalcemic levels in high-risk neonates including
infants of diabetic mothers, preterm infants and infants with
perinatal asphyxia. The early onset hypocalcemia which
presents within 72 h requires treatment with calcium
supplementation for at least 72 h. In contrast, late onset
hypocalcemia usually presents after 7 days and requires
longer term therapy.
Description
Keywords
Hypocalcemia, Newborn, Therapy
Citation
Jain Ashish, Agarwal Ramesh, Sankar M Jeeva, Deorari Ashok Ashok, Paul Vinod K. Hypocalcemia in the Newborn. Indian Journal of Pediatrics. 2010 Oct; 77 (10): 1123-1128.