Long?Term Performance of Untreated Fresh Autologous Pericardium as a Valve Substitute in Pulmonary Position

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dc.contributor.authorPande, Shantanuen_US
dc.contributor.authorArya, Amitabhen_US
dc.contributor.authorAgarwal, Surendra Ken_US
dc.contributor.authorTewari, Prabhaten_US
dc.contributor.authorKapoor, Adityaen_US
dc.contributor.authorSoni, Neetuen_US
dc.contributor.authorKumar, Sunilen_US
dc.date.accessioned2023-07-14T08:00:24Z
dc.date.available2023-07-14T08:00:24Z
dc.date.issued2022-06
dc.description.abstractBackground:Pulmonary regurgitation is imminent after transannular patch (TAP). We analyze the long?term performance of untreated autologous pericardium (UAP) as valve substitute at pulmonary position in patients requiring TAP. Material and Methods: This cross?sectional study include patients operated between 2007 and 2012 (n = 92). A sample of 19 patients was selected for this study which had a follow?up of more than 3 years. This includes patients with no TAP (n = 4) and with TAP and valve substitute, a monocusp (n = 11) or a tricuspid valve (n = 4) at neopulmonary annulus. Patients underwent echocardiography for assessment of right ventricle function and 18 fluoro?deoxyglucose PET CT scan for measurements of valve substitute at neopulmonary annulus. The target to blood ratio (TBR) of uptake of glucose by monocusp was measured at the cooptation edge of the neopulmonary valve. Results: The median age of the patients is 14 (9 – 37). RV function is preserved (TAPSE 18.9 (10.6 – 22.8)) at a mean follow?up of 4 years (3?9). The measurements of monocusp shows a shrinkage in height of the cusp by 35.5% (70% – 1.0%) and length by 7% (?44% ? +104%). There was less shrinkage observed in patients below 15 years of age. The TBR of monocusp was 0.945 (0.17 – 3.35) with a strong correlation between the TBR values of aortic valve leaflet and monocusp leaflet of same patient. Conclusion: The UAP is functional and successful as a valve substitute at neo pulmonary annulus at long?term follow?up. It has resisted calcification and has shown uptake of glucose in physiological limits.en_US
dc.identifier.affiliationsDepartments of Cardiovascular and Thoracic Surgeryen_US
dc.identifier.affiliationsNuclear Medicineen_US
dc.identifier.affiliationsAnaesthesiologyen_US
dc.identifier.affiliationsCardiology anden_US
dc.identifier.affiliationsRadiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, Indiaen_US
dc.identifier.citationPande Shantanu, Arya Amitabh, Agarwal Surendra K, Tewari Prabhat, Kapoor Aditya, Soni Neetu, Kumar Sunil. Long?Term Performance of Untreated Fresh Autologous Pericardium as a Valve Substitute in Pulmonary Position. Annals of Cardiac Anaesthesia. 2022 Jun; 25(2): 164-170en_US
dc.identifier.issn0974-5181
dc.identifier.issn0971-9784
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/219199
dc.languageenen_US
dc.publisherWolters Kluwer - Medknowen_US
dc.relation.issuenumber2en_US
dc.relation.volume25en_US
dc.source.urihttps://doi.org/10.4103/aca.aca_22_21en_US
dc.subjectHeart valveen_US
dc.subjectpulmonary valveen_US
dc.subjectpulmonary stenosisen_US
dc.titleLong?Term Performance of Untreated Fresh Autologous Pericardium as a Valve Substitute in Pulmonary Positionen_US
dc.typeJournal Articleen_US
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