Study of small intestinal bacterial overgrowth in North Indian patients with irritable bowel syndrome: a case control study.

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dc.contributor.authorRana, S Ven_US
dc.contributor.authorSinha, S Ken_US
dc.contributor.authorSikander, Aen_US
dc.contributor.authorBhasin, D Ken_US
dc.contributor.authorSingh, Ken_US
dc.date.accessioned2008-01-21en_US
dc.date.accessioned2009-06-04T04:50:01Z
dc.date.available2008-01-21en_US
dc.date.available2009-06-04T04:50:01Z
dc.date.issued2008-01-21en_US
dc.description.abstractBACKGROUND: Approximately 20% of the general population has irritable bowel syndrome. Despite this high prevalence, the cause of irritable bowel syndrome is unknown. There is no data available concerning the prevalence of small intestinal bacterial overgrowth in North Indian patients with irritable bowel syndrome. AIM: This study evaluated the prevalence of small intestinal bacterial overgrowth in patients with irritable bowel syndrome compared with healthy controls. METHODS: This study included 225 consecutive patients of irritable bowel syndrome between the ages 20 and 65 years attending the gastroenterology clinics. Diagnosis of irritable bowel syndrome was made according to the Rome II criteria. Small intestinal bacterial overgrowth was estimated by using the non-invasive glucose hydrogen breath test. RESULTS: Of 225 patients of irritable bowel syndrome, 160 (71.1%) were male and 65 (28.9%) were female. Of 100 controls, 65 (65%) were male and 35 (35%) female. The prevalence of small intestinal bacterial overgrowth was 25 of 225 (11.1%) patients with irritable bowel syndrome and 1 of 100 (1%) in apparently healthy controls. This difference was statistically significant. The prevalence of small intestinal bacterial overgrowth in male and female patients was not significantly different. CONCLUSION: This study indicates that the prevalence of small intestinal bacterial overgrowth in irritable bowel syndrome patients from North India is approximately 11.1%, which is lower than the reported prevalence.en_US
dc.description.affiliationDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. svrana25@hotmail.comen_US
dc.identifier.citationRana SV, Sinha SK, Sikander A, Bhasin DK, Singh K. Study of small intestinal bacterial overgrowth in North Indian patients with irritable bowel syndrome: a case control study. Tropical Gastroenterology. 2008 Jan-Mar; 29(1): 23-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/125177
dc.language.isoengen_US
dc.source.urihttps://www.tropicalgastro.comen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshBacterial Infections --complicationsen_US
dc.subject.meshBreath Testsen_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshChi-Square Distributionen_US
dc.subject.meshFemaleen_US
dc.subject.meshGlucose --analysisen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshIntestine, Small --microbiologyen_US
dc.subject.meshIrritable Bowel Syndrome --epidemiologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPrevalenceen_US
dc.titleStudy of small intestinal bacterial overgrowth in North Indian patients with irritable bowel syndrome: a case control study.en_US
dc.typeJournal Articleen_US
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