Short-term outcomes of micropulse transscleral cyclophotocoagulation as a primary versus additional therapy in eyes with uncontrolled glaucoma

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dc.contributor.authorRajendrababu, Sharmilaen_US
dc.contributor.authorSenthilkumar, Vijayalakshmi Aen_US
dc.contributor.authorTara, Techi Dodumen_US
dc.contributor.authorUduman, Mohammed Sithiqen_US
dc.contributor.authorAila, Laxmi Ananyaen_US
dc.contributor.authorShukla, Aakriti Gargen_US
dc.date.accessioned2023-08-25T06:35:46Z
dc.date.available2023-08-25T06:35:46Z
dc.date.issued2023-01
dc.description.abstractPurpose: To study the safety and efficacy outcomes of Micropulse Transscleral Cyclophotocoagulation (MP?TSCPC) as a primary versus additional therapy in eyes with uncontrolled glaucoma. Methods: This was a prospective, interventional, comparative study. All patients with advanced and refractory glaucoma treated with MP?TSCPC from April 2020 to December 2020 were recruited in this study. Results: A total of 77 eyes of 77 patients were analyzed. Group A (n = 33), included patients with advanced glaucoma at high risk for invasive surgery, who underwent MP?TSCPC as the primary intervention, and group B (n = 44) included patients who had undergone previous surgical intervention and MP?TSCPC was used additionally to control the intraocular pressure (IOP). Mean IOP and mean number of antiglaucoma medications were 34.06 (13.9) mmHg and 3.64 (0.7), respectively, in group A and 35.61 (11.5) mmHg and 3.73 (0.9), respectively, in Group B. Postoperatively, the mean IOP and percentage of IOP reduction were significantly lower at 1, 3, and 6 months, that is, 20.78 (32%), 22.07 (30%), and 19.09 (37%), respectively, in group A and 23.68 (35%), 19.50 (44%), and 19.61 (42%), respectively, in group B, but there was no difference between the groups at all visits. Postoperative need for ocular hypotensive drugs did not differ in group A (P = 0.231); however, it was significantly lower in group B (P = 0.027). Group A had 87%, 77%, and 74% success rates at 1, 3, and 6 months, respectively, whereas group B had 91%, 86%, and 77% success rates at 1, 3, and 6 months, respectively. Postoperative complications and intervention did not reveal any statistical difference between the two groups. Conclusion: MP?TSCPC may be considered as a temporizing measure both as a primary or as an additional intervention to control the IOP in eyes with refractory and advanced glaucoma that have a high risk of vision?threatening complications with invasive surgery.en_US
dc.identifier.affiliationsDepartment of Glaucoma, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Madurai, Tamil Nadu, Indiaen_US
dc.identifier.affiliationsDepartment of Biostatistics, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Madurai, Tamil Nadu, Indiaen_US
dc.identifier.affiliationsDepartment of Ophthalmology, Wills Eye Hospital, Glaucoma Services, Philadelphia, United Statesen_US
dc.identifier.citationRajendrababu Sharmila, Senthilkumar Vijayalakshmi A, Tara Techi Dodum, Uduman Mohammed Sithiq, Aila Laxmi Ananya, Shukla Aakriti Garg. Short-term outcomes of micropulse transscleral cyclophotocoagulation as a primary versus additional therapy in eyes with uncontrolled glaucoma. Indian Journal of Ophthalmology. 2023 Jan; 71(1): 140-145en_US
dc.identifier.issn1998-3689
dc.identifier.issn0301-4738
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/224781
dc.languageenen_US
dc.publisherAll India Ophthalmological Societyen_US
dc.relation.issuenumber1en_US
dc.relation.volume71en_US
dc.source.urihttps://doi.org/10.4103/ijo.IJO_1289_22en_US
dc.subjectAdvanced glaucomaen_US
dc.subjectmicropulse diode laseren_US
dc.subjectmicropulse transscleral cyclophotocoagulationen_US
dc.subjectrefractory glaucomaen_US
dc.titleShort-term outcomes of micropulse transscleral cyclophotocoagulation as a primary versus additional therapy in eyes with uncontrolled glaucomaen_US
dc.typeJournal Articleen_US
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