Polycystic ovarian syndrome and insulin resistance: a North Indian study.

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dc.contributor.authorAgarwal, Nitin
dc.contributor.authorGangopadhyay, Sukanya
dc.contributor.authorKoch, Nirensingh
dc.contributor.authorGupta, Akash
dc.contributor.authorBatra, Aruna
dc.contributor.authorKabi, B C
dc.date.accessioned2015-11-20T10:38:52Z
dc.date.available2015-11-20T10:38:52Z
dc.date.issued2015-06
dc.description.abstractBackground: Polycystic ovarian syndrome (PCOS) is most common form of chronic anovulation associated with androgen excess. Insulin resistance (IR) is characterized by impaired glucose response to specific amount of insulin. The objective of the study was to find an association between PCOS and IR in North Indian patients. Methods: A total of 50 PCOS cases diagnosed according to Rotterdam criteria, 2003, i.e. at least two of the following three features: oligomenorrhea or amenorrhea, clinical or biochemical hyperandrogenism and polycystic ovaries on ultrasound. Serum glucose levels were measured spectrophotometrically by glucose oxidase-peroxidase method. Insulin levels in serum were estimated by using ELISA based kit procured form Diasorin Ltd, Germany. Homeostatic Model Assessment- Insulin Resistance (HOMA-IR) and Body Mass Index (BMI) were calculated by their formulas. Results: PCOS patients had significantly higher values of BMI, fasting serum glucose, fasting serum insulin and HOMA-IR. Fasting serum glucose was however in the normal range in both cases and control. Conclusion: Our study suggested a strong association of PCOS with insulin resistance in this part of the country.en_US
dc.identifier.citationAgarwal Nitin, Gangopadhyay Sukanya, Koch Nirensingh, Gupta Akash, Batra Aruna, Kabi B C. Polycystic ovarian syndrome and insulin resistance: a North Indian study. International Journal of Research in Medical Sciences. 2015 June; 3(6): 1321-1324.en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/166172
dc.language.isoenen_US
dc.source.urihttps://www.msjonline.org/?mno=186146en_US
dc.subjectPolycystic ovarian syndromeen_US
dc.subjectInsulin resistanceen_US
dc.subjectType II diabetes mellitusen_US
dc.subjectHOMA-IRen_US
dc.titlePolycystic ovarian syndrome and insulin resistance: a North Indian study.en_US
dc.typeArticleen_US
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