Sufficient versus deficient rims during percutaneous closure of ostium secundum type atrial septal defect: A systematic review and meta-analysis

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dc.contributor.authorContreras, Alejandro E.en_US
dc.contributor.authorLedesma, Facundoen_US
dc.contributor.authorPeirone, Alejandro R.en_US
dc.contributor.authorJuaneda, Ernestoen_US
dc.contributor.authorDefago, Victoren_US
dc.contributor.authorCuestas, Eduardoen_US
dc.date.accessioned2023-07-21T11:37:10Z
dc.date.available2023-07-21T11:37:10Z
dc.date.issued2023-04
dc.description.abstractBackground: The aim of this meta-analysis was to compare the efficacy and adverse events of percutaneous occlusion among patients with sufficient and deficient rims. Methods: A systematic review of all articles published in the Pubmed, MEDLINE and Google Scholar databases was performed. Odds ratio (OR) and 95% CI were used as a measure of effect of the combination of studies. I2 with 95% CI was estimated to assess study heterogeneity. For the meta-analysis, a random effects model was used. Results: The systematic search identified ten studies which included 4355 patients; 2661 of those had sufficient rim and the remaining 1694 patients showed some rim deficiency. Implant failure rate was 4.13% CI 95% 3.53e4.72%. Compared to frequency of failures in the group with a deficient rim (5.43% CI 95% 4.35e6.50%), implant failure in patients with a sufficient rim was significantly lower (3.30% CI 95% 2.62e3.97%), OR 2.27 CI 1.34e3.83 (p 0.002). The combined adverse events were 5.19% CI 95% 4.22e6.35% vs 2.7% CI 95% 2.08e3.31% in the deficient vs sufficient rim groups respectively (OR 2.21 CI 0.93e5.29; p 0.07). Implant failures and adverse events were more frequent in patients with posterior inferior rim deficiency. Conclusion: Patients presenting a posteroinferior rim deficiency are associated to both, an increased incidence of closure failure and a combined adverse events occurrence. More studies on posterior rim deficiency are necessary to ensure the feasibility and safety of the percutaneous approach.en_US
dc.identifier.affiliationsDepartment of Cardiology, Hospital Privado Universitario de Cordoba/Instituto Universitario de Ciencias Biomedicas de Cordoba, Cordoba, Argentinaen_US
dc.identifier.affiliationsDepartment of Pediatrics, Hospital Privado Universitario de Cordoba, Cordoba, Argentinaen_US
dc.identifier.affiliationsDepartment of Pediatric Cardiology, Hospital Privado Universitario de Cordoba, Cordoba, Argentinaen_US
dc.identifier.citationContreras Alejandro E., Ledesma Facundo, Peirone Alejandro R., Juaneda Ernesto, Defago Victor, Cuestas Eduardo. Sufficient versus deficient rims during percutaneous closure of ostium secundum type atrial septal defect: A systematic review and meta-analysis. Indian Heart Journal. 2023 Apr; 75(2): 145-152en_US
dc.identifier.issn0019-4832
dc.identifier.issn2213-3763
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/220974
dc.languageenen_US
dc.publisherCardiological Society of Indiaen_US
dc.relation.issuenumber2en_US
dc.relation.volume75en_US
dc.source.urihttps://doi.org/10.1016/j.ihj.2023.01.008en_US
dc.subjectAtrial septal defecten_US
dc.subjectEfficacyen_US
dc.subjectAdverse eventsen_US
dc.subjectEchocardiographyen_US
dc.titleSufficient versus deficient rims during percutaneous closure of ostium secundum type atrial septal defect: A systematic review and meta-analysisen_US
dc.typeJournal Articleen_US
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