Changes in the activity of some hepatic enzymes during organophosphorus insecticide-acephate (orthene) treatment in albino rats.

dc.contributor.authorPatel, P Ben_US
dc.contributor.authorChakrabarti, C Hen_US
dc.date.accessioned1982-10-01en_US
dc.date.accessioned2009-06-01T05:38:28Z
dc.date.available1982-10-01en_US
dc.date.available2009-06-01T05:38:28Z
dc.date.issued1982-10-01en_US
dc.description.abstractAcephate, an organophosphorus insecticide (60 mg/day/rat) disturbed the carbohydrate metabolism in albino rats (wt. between 100-150 gms). Changes in the enzyme activities in the liver were estimated in the rats after oral administration of Acephate. The specific activities of succinic dehydrogenase was decreased in experimental rats than control. A gradual decrease in blood and liver glutathione was also observed. Increase in total lactate dehydrogenase was also noted. It has been observed that in the liver homogenate of treated rats, the isoenzymes LDH4+5 were increased, LDH1+2 were decreased while LDH3 remain unchanged with respect to control value.en_US
dc.identifier.citationPatel PB, Chakrabarti CH. Changes in the activity of some hepatic enzymes during organophosphorus insecticide-acephate (orthene) treatment in albino rats. Indian Journal of Physiology and Pharmacology. 1982 Oct-Dec; 26(4): 311-6en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/106769
dc.language.isoengen_US
dc.source.urihttps://www.ijpp.comen_US
dc.subject.meshAnimalsen_US
dc.subject.meshFemaleen_US
dc.subject.meshGlutathione --analysisen_US
dc.subject.meshInsecticides --poisoningen_US
dc.subject.meshL-Lactate Dehydrogenase --analysisen_US
dc.subject.meshLiver --drug effectsen_US
dc.subject.meshMaleen_US
dc.subject.meshOrganothiophosphorus Compounds --poisoningen_US
dc.subject.meshRatsen_US
dc.subject.meshSuccinate Dehydrogenase --antagonists & inhibitorsen_US
dc.titleChanges in the activity of some hepatic enzymes during organophosphorus insecticide-acephate (orthene) treatment in albino rats.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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