Elucidation of Analgesic and Antipyretic activities of Ficus bengalensis linn. Leaves in rats.
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Date
2011-03
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Abstract
The aim of this study was to investigate the analgesic, antipyretic properties of the various
(chloroform, ethanol and water) extracts from leaf of Ficus bengalensis (Moraceae) in rats. Dose
of the different extracts 200mg/kg, i.p. were significantly reduced (p<0.05). The analgesic activity
of leaf of Ficus bengalensis was studied using hot-plate method and tail-immersion method in
rats. The antipyretic activity of leaf of Ficus bengalensis was studied in Brewer’s yeast-induced
pyrexia in rats. Ethanolic extract of leaf of Ficus bengalensis showed more significant activity,
while, chloroform extract and water extract does not showed significant (p<0.05) analgesic
activity as compared to standard drug using hot-plate method and by tail-immersion method.
Extracts obtained were also subjected to evaluate antipyretic activity by yeast induced fevered
rats. Aspirin (100mg/kg) was taken as standard drug. Water and chloroform extract showed
significant decrease in elevated body temperature, while ethanol extract did not showed a
significant (p<0.05) decrease in elevated body temperature as compared to standard drug.
Description
Keywords
Ficus bengalensis, analgesic, pyrexia, aspirin
Citation
Yadav Sachdev, Kulshreshtha Mayank, Goswami Mradul, Rao Chandana V, Sharma Veena. Elucidation of Analgesic and Antipyretic activities of Ficus bengalensis linn. Leaves in rats. Journal of Applied Pharmaceutical Science. 2011 Mar; 1(1): 38-41.