Biochemical abnormalities in neonatal seizures.

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dc.contributor.authorKumar, Aen_US
dc.contributor.authorGupta, Ven_US
dc.contributor.authorKachhawaha, J Sen_US
dc.contributor.authorSingla, P Nen_US
dc.date.accessioned1995-04-01en_US
dc.date.accessioned2009-05-27T05:05:39Z
dc.date.available1995-04-01en_US
dc.date.available2009-05-27T05:05:39Z
dc.date.issued1995-04-01en_US
dc.description.abstractEarly diagnosis and appropriate treatment of biochemical abnormalities accompanying neonatal seizures is important for effective seizure control and to avoid further brain damage. The present study was carried out on 35 neonates to determine the frequency of various biochemical abnormalities in neonatal seizures. Diagnostic evaluation included estimation of levels of serum calcium, phosphorus, magnesium, sodium, potassium, zinc, and blood glucose. Two-thirds of the neonates with seizures had biochemical disturbances in their sera. A variety of abnormalities occurred in asphyxiated infants, including hyponatremia, hypoglycemia, hypocalcemia, and hypomagnesemia. Primary metabolic disorders accounted for one-forth of the cases of neonatal seizures, the most common being hypoglycemia, hypoglycemia/hypocalcemia, and hypocalcemia/hyperphosphatemia. Inappropriate intrauterine growth, inadequate feeding, and feeding with cow's milk were the main risk factors for primary metabolic seizures. Hyponatremia was a frequent finding in seizures resulting from brain damage like birth asphyxia, meningitis, and intracranial hemorrhage. No infant had hypernatremia, hyperkalemia, hypokalemia, or low serum zinc.en_US
dc.description.affiliationDepartment of Pediatrics, Institute of Medical Sciences, Varanasi.en_US
dc.identifier.citationKumar A, Gupta V, Kachhawaha JS, Singla PN. Biochemical abnormalities in neonatal seizures. Indian Pediatrics. 1995 Apr; 32(4): 424-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/8123
dc.language.isoengen_US
dc.source.urihttps://indianpediatrics.neten_US
dc.subject.meshBiochemical Phenomenaen_US
dc.subject.meshBiochemistryen_US
dc.subject.meshHumansen_US
dc.subject.meshIndiaen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshInfant, Newborn, Diseases --blooden_US
dc.subject.meshMetabolic Diseases --blooden_US
dc.subject.meshPrognosisen_US
dc.subject.meshSeizures --blooden_US
dc.titleBiochemical abnormalities in neonatal seizures.en_US
dc.typeJournal Articleen_US
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