Thyrotoxicosis--treatment by I131 therapy and early prediction of hypothyroidism following this therapy.

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dc.contributor.authorKhanna, C Men_US
dc.contributor.authorJain, S Ken_US
dc.contributor.authorWalia, R Pen_US
dc.date.accessioned1994-01-01en_US
dc.date.accessioned2009-05-30T19:25:17Z
dc.date.available1994-01-01en_US
dc.date.available2009-05-30T19:25:17Z
dc.date.issued1994-01-01en_US
dc.description.abstractThis study was undertaken in 68 thyrotoxic patients to assess the predictive value of various post treatment biochemical and immunological tests for early hypothyroidism after I131 therapy and to determine whether pretreatment with carbimazole protects against post I131 therapy hypothyroidism. Early changes observed in serum T3, T4, TSH, thyroid microsomal and thyroglobulin antibody levels were found to be of no predictive value. A sharp increase in TRAb levels around 3 months following I131 therapy indicated that hypothyroidism was likely to occur as this rise reflected a greater degree of thyroid damage. Lower levels of thyroglobulin in patients who became hypothyroid by 12 months after treatment would support this view. Carbimazole pretreatment for eight weeks did not appear to protect against hypothyroidism, in our study.en_US
dc.description.affiliationDept of Endocrinology, Institute of Nuclear Medicine & Allied Sciences, Delhi.en_US
dc.identifier.citationKhanna CM, Jain SK, Walia RP. Thyrotoxicosis--treatment by I131 therapy and early prediction of hypothyroidism following this therapy. Journal of the Association of Physicians of India. 1994 Jan; 42(1): 36-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/86759
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAntibodies --analysisen_US
dc.subject.meshCarbimazole --therapeutic useen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshForecastingen_US
dc.subject.meshHumansen_US
dc.subject.meshHypothyroidism --blooden_US
dc.subject.meshIodine Radioisotopes --adverse effectsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPremedicationen_US
dc.subject.meshRadiation Injuries --blooden_US
dc.subject.meshRadiation-Protective Agents --therapeutic useen_US
dc.subject.meshReceptors, Thyrotropin --immunologyen_US
dc.subject.meshThyroglobulin --immunologyen_US
dc.subject.meshThyrotoxicosis --radiotherapyen_US
dc.subject.meshThyrotropin --blooden_US
dc.subject.meshThyroxine --blooden_US
dc.subject.meshTriiodothyronine --blooden_US
dc.titleThyrotoxicosis--treatment by I131 therapy and early prediction of hypothyroidism following this therapy.en_US
dc.typeJournal Articleen_US
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