Efficacy of two different DEC regimens in the treatment of human filarial infection.

Simple item page
dc.contributor.authorPrasad, G Ben_US
dc.contributor.authorRamaprasad, Pen_US
dc.contributor.authorRao, V Sen_US
dc.contributor.authorBharati, M Sen_US
dc.contributor.authorHarinath, B Cen_US
dc.date.accessioned1990-03-01en_US
dc.date.accessioned2009-05-27T06:40:23Z
dc.date.available1990-03-01en_US
dc.date.available2009-05-27T06:40:23Z
dc.date.issued1990-03-01en_US
dc.description.abstractTwo regimens of diethyl carbamazine (DEC) viz., 14 day and 5 day, were compared for microfilaricidal effect and side effects, in the treatment of bancroftian filariasis. The rate of successful treatment, cure rate and decrease in mf count were found to be significantly high with the 14 days regimen when assessed immediately after treatment. About 40 per cent of subjects on the 14 days regimen and 66 per cent of patients on 5 days regimen experienced side reactions. The severity of side reactions was more in patients on 5 days regimen. When the effect of DEC was assessed one year after treatment with the 14 days regimen and compared with the results immediately after treatment, the rate of successful treatment, cure rate and decrease in mf count were reduced significantly. The 14 days DEC regimen with initial low dose of DEC along with antipyretics may be better accepted in the control programmes of filariasis.en_US
dc.description.affiliationDepartment of Biochemistry, Mahatma Gandhi Institute of Medical Sciences, Wardha.en_US
dc.identifier.citationPrasad GB, Ramaprasad P, Rao VS, Bharati MS, Harinath BC. Efficacy of two different DEC regimens in the treatment of human filarial infection. Indian Journal of Medical Research. 1990 Mar; 91(): 133-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/17378
dc.language.isoengen_US
dc.source.urihttps://icmr.nic.in/ijmr/ijmr.htmen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAnimalsen_US
dc.subject.meshChilden_US
dc.subject.meshDiethylcarbamazine --therapeutic useen_US
dc.subject.meshElephantiasis, Filarial --drug therapyen_US
dc.subject.meshFemaleen_US
dc.subject.meshFilariasis --drug therapyen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshWuchereria bancroftien_US
dc.titleEfficacy of two different DEC regimens in the treatment of human filarial infection.en_US
dc.typeClinical Trialen_US
dc.typeComparative Studyen_US
dc.typeControlled Clinical Trialen_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Indian Journal of Medical Research