Effects of dexmedetomidine for retrobulbar anesthesia in orbital ball implants after enucleation surgery.
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Date
2015-09
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Abstract
Background: Dexmedetomidine (DEX) can prolong the duration of local anesthetics, but the use of
retrobulbar DEX has not been fully elucidated. This study was designed to determine the effects of adding
DEX to lidocaine‑bupivacaine for retrobulbar block in orbital ball implants after enucleation surgery.
Materials and Methods: A total of 200 patients of both sexes aged 30–60 years of American Society of
Anesthesiologists I and II, scheduled for orbital ball implants after enucleation surgery, were enrolled
for the study. Patients were randomly assigned into one of the two groups: Control (n = 100) received
lidocaine‑bupivacaine retrobulbar block, DEX (n = 100) received lidocaine‑bupivacaine plus 1 ug/kg DEX
retrobulbar block. Hemodynamic data, duration of motor and sensory blocks, pain by visual analog
scale, bispectral index (BIS), side effects, consumption of dezocine as a rescue analgesic, patient and
surgeon satisfaction were recorded. Results: Duration of analgesia was prolonged in the DEX, compared
with the control group ([258.35 ± 66.82 min] as [130.75 ± 29.52 min], [P < 0.05]). The median number of
postoperative analgesic requests per patient during the first 24 h was decreased in the DEX group (P < 0.05).
In the first 24 postoperative hours, DEX group consumed significantly less dezocine (P < 0.05). BIS values
and mean arterial pressure remained lower in the DEX group, but within the safe range (P < 0.05). The
side effect profile was similar between the two groups. Patients and surgeon satisfaction were higher
in the DEX group (P < 0.05). Demographic characteristics were comparable in both groups (P > 0.05).
Conclusion: Retrobulbar DEX reduces consumption of rescue analgesic, prolonged the duration of
retrobulbar block, improved postoperative pain, provided better sedation effects, and increased patient and
surgeon satisfaction after orbital ball implants after enucleation surgery.
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Keywords
Dexmedetomidine, orbital ball implants after enucleation surgery, retrobulbar block
Citation
Ye Weidi, Hu Zhiyong, Jin Xiuming, Wang Pei. Effects of dexmedetomidine for retrobulbar anesthesia in orbital ball implants after enucleation surgery. Indian Journal of Ophthalmology. 2015 Sept; 63(9): 704-709.