Correlation between CD4 count and intensity of Candida colonization in the oropharynx of HIV-infected/ AIDS patient.

Simple item page
dc.contributor.authorBandar, Ivo Novita Sahen_US
dc.contributor.authorWidodo, Djokoen_US
dc.contributor.authorDjauzi, Samsuridjalen_US
dc.contributor.authorMuthalib, Abdulen_US
dc.contributor.authorSoegondo, Sidartawanen_US
dc.contributor.authorWahyuningsih, Retnoen_US
dc.date.accessioned2006-07-06en_US
dc.date.accessioned2009-05-28T04:37:19Z
dc.date.available2006-07-06en_US
dc.date.available2009-05-28T04:37:19Z
dc.date.issued2006-07-06en_US
dc.description.abstractAIM: To know the correlation between CD4 count and intensity of Candida colonizations in the oropharynx of HIV-infected/AIDS patients, to get the prevalence of oropharyngeal candidiasis (OPC), and to know what kind of Candida species that causes oropharynx candidiasis of HIV-infected/AIDS patients. METHODS: A cross-sectional study was conducted in HIV-infected/AIDS patients who came as outpatients and inpatients in Cipto Mangunkusumo Hospital. The patients were interviewed, physically examined, their CD4 counts were checked, and their mouth rinse samples were taken to be cultured. Candida species was identified in CHROMagar media, and data were processed. RESULTS: From September 2004 until January 2005, 60 HIV-infected/AIDS patients were included in this study. There were 86.7% males and 13.3% females. Majority of the patients were from 20-30 years age group (85%). The most frequent transmission was among drug users (75%) followed by sexual contact (18.3%). The median of CD4 counts was 100 cells/il, ranged from 2 to 842 cells/il. Proportion of the OPC was 63.3% (CI 95% = 51.1 - 75.5). From 59 Candida isolates in this study, 74.58% were C. albicans. Candida non C. albicans species that were found in this trial were C. krusei, C. parapsilosis and C. tropicalis. There was significant correlation between low CD4 counts and high intensity of Candida colonization on the oropharynx of the subjects (r = -0.756). CONCLUSION: There was strong negative correlation (r = -0.756) between CD4 count and intensity of Candida colonization in the oropharynx of HIV-infected/AIDS patients. Proportion of OPC in this study was 63.3%. The most frequent species found in the oropharynx of the subjects was C. albicans.en_US
dc.description.affiliationDepartement of Internal Medicine, Faculty of Medicine, University of Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta.en_US
dc.identifier.citationBandar IN, Widodo D, Djauzi S, Muthalib A, Soegondo S, Wahyuningsih R. Correlation between CD4 count and intensity of Candida colonization in the oropharynx of HIV-infected/ AIDS patient. Acta Medica Indonesiana. 2006 Jul-Sep; 38(3): 119-25en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/47174
dc.language.isoengen_US
dc.subject.meshAIDS-Related Opportunistic Infections --immunologyen_US
dc.subject.meshAdulten_US
dc.subject.meshCD4 Lymphocyte Counten_US
dc.subject.meshCandida --isolation & purificationen_US
dc.subject.meshCandidiasis, Oral --immunologyen_US
dc.subject.meshCross-Sectional Studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshHIV-1en_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshOropharynx --microbiologyen_US
dc.subject.meshPharyngeal Diseases --immunologyen_US
dc.titleCorrelation between CD4 count and intensity of Candida colonization in the oropharynx of HIV-infected/ AIDS patient.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
Files
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.79 KB
Format:
Plain Text
Description:
Download
Collections
Acta Medica Indonesiana