Disabilities in multibacillary leprosy patients: before, during and after multidrug therapy.

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dc.contributor.authorSharma, Pen_US
dc.contributor.authorKar, H Ken_US
dc.contributor.authorBeena, K Ren_US
dc.contributor.authorKaur, Hen_US
dc.contributor.authorNarayan, Ren_US
dc.date.accessioned1996-04-01en_US
dc.date.accessioned2009-05-28T10:17:50Z
dc.date.available1996-04-01en_US
dc.date.available2009-05-28T10:17:50Z
dc.date.issued1996-04-01en_US
dc.description.abstractOne hundred fifty-one patients (125 males and 26 females) of multibacillary leprosy (LL 88, BL 40, BB 23), registered during 1986-1992 for multidrug therapy (MDT), were analysed with reference to their disabilities before, during and after MDT. At induction 48 (31.7%) had no disability (Gr 0), 59 (39.0%) had only peripheral anaesthesia (Gr 1) and 44 (29.1%) had Gr 2 and 3 deformities with or without anaesthesia. The parallel analysis of the three groups, with nearly equal duration of symptoms, revealed that new deformities developed in only a few cases during and after MDT, least in the Gr 0 group. The crude fresh deformity incidence was 59.2 per 1,000 person years of observation. The rate of recovery from anaesthesia was higher (64%) in Gr 1 group than that (44%) in group with Gr 2, 3 deformities. No significant difference was observed between the incidence of Gr 2 deformities developed before, during and after MDT (incidence of claw-hands 9.2% before and 7.9% during and after MDT, trophic ulcers 13.9% before and 17.8% during and after MDT). Out of 19 cases which developed motor weakness during MDT and follow-up, 10 (52.6%) were instances of quite nerve paralysis. Occupational factors influenced the development of deformities but not the sex and bacterial load. Generally, the lower the Grade of disability at induction of patient for MDT, the lower the chances of new disability development and higher the chances of recovery from sensory impairments.en_US
dc.description.affiliationDepartment of Dermatology, STD and Leprosy; Dr Ram Manohar Lohia Hospital, New Delhi.en_US
dc.identifier.citationSharma P, Kar HK, Beena KR, Kaur H, Narayan R. Disabilities in multibacillary leprosy patients: before, during and after multidrug therapy. Indian Journal of Leprosy. 1996 Apr-Jun; 68(2): 127-36en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/55127
dc.language.isoengen_US
dc.subject.meshColony Count, Microbialen_US
dc.subject.meshDisability Evaluationen_US
dc.subject.meshDrug Therapy, Combinationen_US
dc.subject.meshFemaleen_US
dc.subject.meshFoot Deformities, Acquired --etiologyen_US
dc.subject.meshHand Deformities, Acquired --etiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshHypesthesia --etiologyen_US
dc.subject.meshIncidenceen_US
dc.subject.meshLeprostatic Agents --therapeutic useen_US
dc.subject.meshLeprosy --complicationsen_US
dc.subject.meshMaleen_US
dc.subject.meshMuscle Weakness --etiologyen_US
dc.subject.meshNeuritis --etiologyen_US
dc.subject.meshSeverity of Illness Indexen_US
dc.subject.meshSkin Ulcer --etiologyen_US
dc.titleDisabilities in multibacillary leprosy patients: before, during and after multidrug therapy.en_US
dc.typeJournal Articleen_US
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