Evaluation of outcome of various treatment methods for endogenous endophthalmitis.

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dc.contributor.authorKeswani, Tulsien_US
dc.contributor.authorAhuja, Vijayen_US
dc.contributor.authorChangulani, Manishen_US
dc.date.accessioned2006-11-09en_US
dc.date.accessioned2009-05-29T06:18:12Z
dc.date.available2006-11-09en_US
dc.date.available2009-05-29T06:18:12Z
dc.date.issued2006-11-09en_US
dc.description.abstractAIM: To evaluate the role of different treatment methods (intravitreal antibiotics and vitrectomy) for endogenous endophthalmitis and assess the outcome. Materials and0 METHODS: This is a retrospective observational case study. Sixteen cases of endogenous endophthalmitis noted in 14 patients between October 2000 and April 2004 were reviewed. Two patients had bilateral disease. Patients were followed up for a mean of 3 months (range, 1-12 months). RESULTS: Vitreous and aqueous cultures were positive in 8 (66%) cases and 3 (75%) cases respectively. Fungal isolates occurred in 4 (33%) cases, out of which 3 were due to candida, gram-positive isolates occurred in 2 (16%) and gram-negative isolates in 2 (16%) of the cases. Initial treatment included vitreous tap and injection of intravitreal medication in 12 (75%) cases and pars plana vitrectomy with injection of intravitreal medication in 3 (19%) cases. Final visual outcomes were obtainable for13 cases (1 patient died and 1 patient was lost to follow-up and 1 eye was eviscerated). Five (43%) of these cases achieved visual acuity of 6/60 or better and 8 (56%) eyes achieved a visual acuity less than 6/60. Risk factors mainly associated with the disease were uncontrolled diabetes mellitus, chronic renal failure, renal transplant, abdominal surgeries and septicemia. CONCLUSION: Our experience suggests that endogenous endophthalmitis is generally associated with poor visual outcome. Prompt treatment with intravitreal antibiotics and vitrectomy can result in improvement in ocular signs and visual acuity in majority of the patients. The patients with culture-positive endogenous endophthalmitis are more likely to have fungal isolates with a predominance of candida. Fungal endopthalmitis has a poor visual outcome as compared to bacterial endophthalmitis.en_US
dc.description.affiliationNational Institute of Ophthalmology, Pune, India. tulsikes@yahoo.comen_US
dc.identifier.citationKeswani T, Ahuja V, Changulani M. Evaluation of outcome of various treatment methods for endogenous endophthalmitis. Indian Journal of Medical Sciences. 2006 Nov; 60(11): 454-60en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/68653
dc.language.isoengen_US
dc.source.urihttps://www.indianjmedsci.orgen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAnti-Bacterial Agents --therapeutic useen_US
dc.subject.meshBacteria --isolation & purificationen_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshEndophthalmitis --microbiologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshFungi --isolation & purificationen_US
dc.subject.meshHumansen_US
dc.subject.meshIndiaen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshTreatment Outcomeen_US
dc.subject.meshVisual Acuityen_US
dc.subject.meshVitrectomyen_US
dc.subject.meshVitreous Body --microbiologyen_US
dc.titleEvaluation of outcome of various treatment methods for endogenous endophthalmitis.en_US
dc.typeJournal Articleen_US
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