Clinical Profile and Short-term Outcome of Pediatric Status Epilepticus at a Tertiary-care Center in Northern India

Simple item page
dc.contributor.authorChinmay, Chetanen_US
dc.contributor.authorSharma, Suvasinien_US
dc.contributor.authorMathur, Surendra Ben_US
dc.contributor.authorJain, Puneeten_US
dc.contributor.authorAneja, Satinderen_US
dc.date.accessioned2020-04-23T07:45:03Z
dc.date.available2020-04-23T07:45:03Z
dc.date.issued2020-03
dc.description.abstractObjective: To assess clinical profile and short term treatmentoutcomes of pediatric status epilepticus (SE) at a tertiary-carecenter in northern India.Methods: Prospective cohort study enrolled children aged 1month to 18 years presenting with SE to the emergencydepartment. Enrolled children (109) were treated as per hospitalprotocols. Clinical features during hospitalization were noted.Pediatric overall performance category (POPC) scale was usedfor classification of outcome at the time of discharge.Results: Acute symptomatic etiology was identified in 66(60.6%) cases (CNS infections were predominant). Previousdiagnosis of epilepsy was found in 32 (29.4%) children; andbenzodiazepine responsive SE were seen in 65 (59.6%)children. Predictors of unfavorable outcome were acutesymptomatic etiology (adjusted OR 4.50; 95% CI 1.49, 13.62) andno treatment administered prior to hospital (adjusted OR 3.97;95% CI 1.06, 14.81).Conclusions: Acute symptomatic etiology, mainly acute CNSinfections, is the leading cause of SE in this region. Early and pre-hospital management with benzodiazepines may improve SEoutcome.en_US
dc.identifier.affiliationsDivision of Pediatric Neurology, Department of Pediatrics, Lady Hardinge Medical College and associated Kalawati SaranChildren Hospital, New Delhi, Indiaen_US
dc.identifier.citationChinmay Chetan, Sharma Suvasini, Mathur Surendra B, Jain Puneet, Aneja Satinder. Clinical Profile and Short-term Outcome of Pediatric Status Epilepticus at a Tertiary-care Center in Northern India. Indian Pediatrics. 2020 Mar; 57(3): 213-217en_US
dc.identifier.issn0974-7559
dc.identifier.issn0019-6061
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/199499
dc.languageenen_US
dc.publisherIndian Academy of Pediatricsen_US
dc.relation.issuenumber3en_US
dc.relation.volume57en_US
dc.source.urihttps://www.indianpediatrics.net/mar2020/213.pdfen_US
dc.subjectEpilepsy,Etiologyen_US
dc.subjectSeizuresen_US
dc.subjectTreatmenten_US
dc.titleClinical Profile and Short-term Outcome of Pediatric Status Epilepticus at a Tertiary-care Center in Northern Indiaen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ip2020v57n3p213.pdf
Size:
31.45 KB
Format:
Adobe Portable Document Format
Download
Collections
Indian Pediatrics