The difference between mean plasma levels of von Willebrand factor and platelet aggregation in type 2 diabetes mellitus with and without peripheral vascular disease at sardjito general hospital, yogyakarta.

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dc.contributor.authorRenaldi, Ollyen_US
dc.contributor.authorAsdie, Rizka Hen_US
dc.contributor.authorSinorita, Hemien_US
dc.contributor.authorPramono, Bowoen_US
dc.contributor.authorPurnomo, Luthfan Ben_US
dc.date.accessioned2009-04-25en_US
dc.date.accessioned2009-05-28T04:29:13Z
dc.date.available2009-04-25en_US
dc.date.available2009-05-28T04:29:13Z
dc.date.issued2009-04-25en_US
dc.description.abstractAim: to determine the differences in mean plasma values of von Willebrand factor and platelet aggregation in type 2 DM patient with or without peripheral arterial disease. Methods: this is a cross-sectional study, conducted from August to December 2006, in Dr. Sardjito General Hospital Yogyakarta, on type 2 DM patients, aged 50 years and above, and signed the informed consent. The exclusion criteria are cardiac failure, renal insufficiency (creatinine clearance <30 ml/minute), malignancy, acute disease, decrease hepatic function, having ulcer or DM gangrene, amputation, taking multivitamine and/or antiplatelet, and smoking. All samples that matched inclusion criteria were divided into 2 groups: with peripheral arterial disease and without peripheral arterial disease. The data of subjects are presented as mean and standard deviation and proportion. Variables with numeric data are analized with the student t-test for normal distribution and with Mann-Whitney U-test for abnormal distribution. Significancy limit was set at p value of <0,05. Statistical analysis was done by using SPSS 11.5 software. Results: there were 17 subjects having PVD. There were no significantly differences of mean vWF plasma levels (140.544 + 76,137% vs. 133.325 + 53,246%) and platelet aggregation (87.741 + 19.886% vs. 93.981 + 10.138%) between type 2 DM with and without PVD (p >0.05). Conclusion: there were no statistically difference in mean vWF plasma levels and platelet aggregation between type 2 diabetes mellitus with and without PVD.en_US
dc.description.affiliationDepartment of Internal Medicine, Faculty of Medicine, Gadjah Mada University - Dr. Sardjito Hospital. Jl. Kesehatan Sekip no. 1, Yogyakarta, Indonesia.en_US
dc.identifier.citationRenaldi O, Asdie RH, Sinorita H, Pramono B, Purnomo LB. The difference between mean plasma levels of von Willebrand factor and platelet aggregation in type 2 diabetes mellitus with and without peripheral vascular disease at sardjito general hospital, yogyakarta. Acta Medica Indonesiana. 2009 Apr; 41(2): 54-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/46951
dc.language.isoengen_US
dc.subject.meshDiabetes Mellitus, Type 2en_US
dc.subject.meshPlatelet Aggregationen_US
dc.subject.meshPeripheral Vascular Diseasesen_US
dc.subject.meshvon Willebrand Factoren_US
dc.subject.meshCross-Sectional Studiesen_US
dc.titleThe difference between mean plasma levels of von Willebrand factor and platelet aggregation in type 2 diabetes mellitus with and without peripheral vascular disease at sardjito general hospital, yogyakarta.en_US
dc.typeJournal Articleen_US
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