Minimum inhibitory concentration of squid ink Loligo sp. extract on growth of Staphylococcus aureus and Streptococcus mutans bacteria

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dc.contributor.authorPangemanan, Damajanty H. C.en_US
dc.contributor.authorMintjelungan, Christyen_US
dc.date.accessioned2020-11-18T10:01:03Z
dc.date.available2020-11-18T10:01:03Z
dc.date.issued2020-03
dc.description.abstractBackground: Dental caries and periodontal disease can be caused by bacteria that attack hard and soft tissues in the oral cavity like Staphylococcus aureus and Streptococcus mutans bacteria One way to prevent infections caused by the bacteria are by using mouthwash. Currently, mouthwash that is widely used is mouthwash containing chlorhexidine, which has side effects in the form of tooth staining when used prolonged. The need for alternative medicines from nature that effectively cope with polymicrobial infections. One of the marine products that has pharmaceutical properties is squid, especially the ink it produces.Methods: This research is a pure experimental study (true experimental design) with a randomized pretest-posttest control group design. Squid ink Loligo sp. extract, obtained by extracting squid ink Loligo sp., with maceration method using 96% ethanol solvent. This research uses serial dilution method with spectrophotometric testing method.Results: After measuring the turbidity value in each treatment tube, it was found that at a concentration of 1.56% squid ink Loligo sp. extract began to inhibit the growth of Staphylococcus aureus and Streptococcus mutans bacteria.  This is proven because the absorbance value after and before incubation is fixed.Conclusions: The minimum inhibitory concentration of squid ink Loligo sp. extract on the growth of Staphylococcus aureus and Streptococcus mutants at a concentration of 1.56%.en_US
dc.identifier.affiliationsDepartment of Physiology, Faculty of Medicine, Sam Ratulangi University, Manado, North Sulawesi, Indonesiaen_US
dc.identifier.affiliationsDepartment of Public Dental Hygiene, Dentistry Study Program, Faculty of Medicine, Sam Ratulangi University, Manado, North Sulawesi, Indonesiaen_US
dc.identifier.citationPangemanan Damajanty H. C., Mintjelungan Christy. Minimum inhibitory concentration of squid ink Loligo sp. extract on growth of Staphylococcus aureus and Streptococcus mutans bacteria. International Journal of Research in Medical Sciences. 2020 Mar; 8(3): 801-805en_US
dc.identifier.issn2320-6071
dc.identifier.issn2320-6012
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/212157
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber3en_US
dc.relation.volume8en_US
dc.source.urihttps://dx.doi.org/10.18203/2320-6012.ijrms20200529en_US
dc.subjectMinimum inhibitory concentrationen_US
dc.subjectSquid ink Loligo sp.en_US
dc.subjectStaphylococcus aureusen_US
dc.subjectStreptococcus mutansen_US
dc.titleMinimum inhibitory concentration of squid ink Loligo sp. extract on growth of Staphylococcus aureus and Streptococcus mutans bacteriaen_US
dc.typeJournal Articleen_US
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