Outcome in childhood guillain-barré syndrome.

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dc.contributor.advisorGuillain-Barre Syndrome --therapy
dc.contributor.authorKalra, Veena
dc.contributor.authorSankhyan, Naveen
dc.contributor.authorSharma, Suvasini
dc.contributor.authorGulati, Sheffali
dc.contributor.authorChoudhry, Rama
dc.contributor.authorDhawan, Benu
dc.date.accessioned2012-10-22T06:11:12Z
dc.date.available2012-10-22T06:11:12Z
dc.date.issued2009-08
dc.description.abstractTo assess the outcome of children diagnosed with Guillain-Barré syndrome (GBS), followed up for a median duration of 25 months. Methods. Tertiary center, prospective follow up of children with GBS enrolled from Dec 2003 through Sep 2006. Functional recovery was determined at 12 months and later using Hughes scale (0-6). Clinical, electrophysiological variables were compared between the good outcome (grade 0/1) and bad outcome groups (died or functional grade >1). Results. Among 52 children with a median age of five yr there was male preponderance (75.4%). Mortality during acute phase was 11.5% (6/52). Among the survivors long term data was obtainable in 40 of the 46 children. At one year follow up 87.5% children had fully recovered or had minimal symptoms, beyond one year this rose to 95%. Only 2 among 40 had significant symptoms at last follow up (1 grade-2 and 1 grade-3). Factors significantly associated with poor outcome were: need for artificial ventilation, inexitable nerves on nerve conduction testing and delayed independent walking. Conclusion. Children needing ventilation have the worst short-term prognosis. However, irrespective of severity during acute phase, good long-term recovery can be expected in most children.en_US
dc.identifier.citationKalra Veena, Sankhyan Naveen, Sharma Suvasini, Gulati Sheffali, Choudhry Rama, Dhawan Benu. Outcome in childhood guillain-barré syndrome. Indian Journal of Pediatrics. 2009 Aug; 76(8): 795-799.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/142342
dc.language.isoenen_US
dc.source.urihttps://medind.nic.in/icb/t09/i8/icbt09i8p795.pdfen_US
dc.subjectPrognosisen_US
dc.subjectOutcomeen_US
dc.subjectGBSen_US
dc.subjectAcute polyneuropathyen_US
dc.subject.meshAdolescent
dc.subject.meshChild
dc.subject.meshChild, Preschool
dc.subject.meshFemale
dc.subject.meshFollow-Up Studies
dc.subject.meshGuillain-Barre Syndrome --diagnosis
dc.subject.meshGuillain-Barre Syndrome --mortality
dc.subject.meshHumans
dc.subject.meshInfant
dc.subject.meshGuillain-Barre Syndrome --therapy
dc.subject.meshLogistic Models
dc.subject.meshMale
dc.subject.meshPrognosis
dc.subject.meshProspective Studies
dc.subject.meshRecovery of Function
dc.subject.meshSeverity of Illness Index
dc.subject.meshStatistics, Nonparametric
dc.subject.meshTreatment Outcome
dc.titleOutcome in childhood guillain-barré syndrome.en_US
dc.typeArticleen_US
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