The treatment of kala-azar during pregnancy.

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dc.contributor.authorThakur, C Pen_US
dc.contributor.authorSinha, G Pen_US
dc.contributor.authorSharma, Ven_US
dc.contributor.authorBarat, Den_US
dc.date.accessioned1993-11-01en_US
dc.date.accessioned2009-06-03T07:28:07Z
dc.date.available1993-11-01en_US
dc.date.available2009-06-03T07:28:07Z
dc.date.issued1993-11-01en_US
dc.description.abstractBACKGROUND. Kala-azar in pregnant women is difficult to treat because for them the two commonly used drugs, sodium stibogluconate and pentamidine, are not considered safe. We assessed the effect of amphotericin B on pregnancy, on the foetus and kala-azar. METHODS. Five pregnant women were administered amphotericin B at a dose of 1 mg/kg body weight daily starting with 0.5 mg/kg body weight till a total dose of 20 mg/kg body weight was given. The progress of pregnancy was monitored ultrasonographically and the mothers and children were followed for six months. RESULTS. All the 5 women were cured of the disease and there was no harmful effect on the children. CONCLUSION. Amphotericin B cures kala-azar during pregnancy with no harmful effects on the foetus.en_US
dc.description.affiliationDepartment of Medicine, Patna Medical College, Bihar, India.en_US
dc.identifier.citationThakur CP, Sinha GP, Sharma V, Barat D. The treatment of kala-azar during pregnancy. National Medical Journal of India. 1993 Nov-Dec; 6(6): 263-5en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/119737
dc.language.isoengen_US
dc.source.urihttps://www.nmji.inen_US
dc.subject.meshAdulten_US
dc.subject.meshAmphotericin B --therapeutic useen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLeishmaniasis, Visceral --drug therapyen_US
dc.subject.meshPregnancyen_US
dc.subject.meshPregnancy Complications, Parasitic --drug therapyen_US
dc.titleThe treatment of kala-azar during pregnancy.en_US
dc.typeCase Reportsen_US
dc.typeJournal Articleen_US
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