Clinical, angiographic and histopathological predictors of restenosis after directional coronary atherectomy.

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dc.contributor.authorPetkar, Sen_US
dc.contributor.authorGambhir, D Sen_US
dc.contributor.authorTrehan, Ven_US
dc.contributor.authorNair, Men_US
dc.contributor.authorGondal, Ren_US
dc.contributor.authorMalhotra, Ven_US
dc.contributor.authorKhalilullah, Men_US
dc.date.accessioned1995-05-01en_US
dc.date.accessioned2009-05-27T04:22:55Z
dc.date.available1995-05-01en_US
dc.date.available2009-05-27T04:22:55Z
dc.date.issued1995-05-01en_US
dc.description.abstractOut of 127 directional coronary atherectomy (DCA) procedures done in our laboratory, there were 81 patients who had completed a minimum of six months of follow-up. To study the factors predisposing restenosis after successful DCA, we analysed the clinical and angiographic profile of the patients and the histopathological findings of the excised tissue in 44 patients whose complete follow-up data was available with us. The indication of DCA was an extremely eccentric significant stenosis located in the proximal or midsegment of a large vessel (> or = 3 mm size) in 97 percent of the cases. Angiographic restenosis, defined as more than 50 percent luminal diameter stenosis was absent in 24 (54.5%, Group A) and present in 20 (45.5%, Group B) patients. On univariate analysis, the factors which predisposed to restenosis were: (i) left anterior descending location, (ii) longer lesion length (9.6 +/- 3.1 mm vs 5.2 +/- 1.6, p < 0.01) and (iii) greater post-procedure residual luminal diameter stenosis (13.1 +/- 10.8% vs 4.3 +/- 6%, p < 0.01). No significant difference was found between the two groups for other variables like unstable angina, the location and the morphological characteristics of the lesion and the ratio of the vessel diameter to the size of the Atherocath. Histopathological examination of the retrieved tissue revealed the presence of media with or without external elastic lamina in 8 (33%) patients in Group A--without restenosis compared to only 1 (5%) patients in Group B--with restenosis (p < 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)en_US
dc.description.affiliationDepartment of Cardiology, G.B. Pant Hospital, New Delhi.en_US
dc.identifier.citationPetkar S, Gambhir DS, Trehan V, Nair M, Gondal R, Malhotra V, Khalilullah M. Clinical, angiographic and histopathological predictors of restenosis after directional coronary atherectomy. Indian Heart Journal. 1995 May-Jun; 47(3): 227-31en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/4395
dc.language.isoengen_US
dc.source.urihttps://indianheartjournal.comen_US
dc.subject.meshAtherectomy, Coronaryen_US
dc.subject.meshCoronary Angiographyen_US
dc.subject.meshCoronary Disease --pathologyen_US
dc.subject.meshCoronary Vessels --pathologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshFollow-Up Studiesen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRecurrenceen_US
dc.titleClinical, angiographic and histopathological predictors of restenosis after directional coronary atherectomy.en_US
dc.typeJournal Articleen_US
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