Exacerbation of Erythema Nodosum Leprosum Possibly Triggered by COVID-19 Vaccine : A Case Repor

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dc.contributor.authorGupta, Sen_US
dc.contributor.authorNarang, Ten_US
dc.contributor.authorChhabra, Sen_US
dc.contributor.authorDogra, Sen_US
dc.date.accessioned2023-08-09T06:22:20Z
dc.date.available2023-08-09T06:22:20Z
dc.date.issued2022-09
dc.description.abstractErythema nodosum leprosum (ENL) is an immune complex mediated type III hypersensitivity reaction seen in patients of borderline lepromatous and lepromatous leprosy. It can be caused by a wide array of triggers and can be seen before, during, or after completion of anti-leprosy therapy. There are multiple well-known triggers for type 2 reactions like the initiation of multidrug therapy, Mantoux testing, vaccination, mental and physical stress, and physiological states like pregnancy. Herein, we report a case of exacerbation of ENL in a middle-aged woman, probably due to COVID-19 vaccine while she was well-controlled on immunosuppressive therapy. The episode was treated with non-steroid anti-inflammatory drugs and oral steroids and the symptoms resolved within 2 weeks. Although causality was highly possible between the occurrence of ENL and COVID-19 vaccine, physicians should be aware that it can be easily managed with proper care and medicines and this should not be a basis for deferring the vaccine.en_US
dc.identifier.affiliations3rd-year Resident (MD, Dermatology, Venereology and Leprology), Department of Dermatology, Venereology and Leprology.en_US
dc.identifier.affiliationsAssociate Professor, Department of Dermatology, Venereology and Leprologyen_US
dc.identifier.affiliationsAssistant Professor, Department of Immunopathologyen_US
dc.identifier.affiliationsProfessor, Department of Dermatology, Venereology and Leprology, Post Graduate Institute of Medical Education and Research, Chandigarh-160012, Indiaen_US
dc.identifier.citationGupta S, Narang T, Chhabra S, Dogra S. Exacerbation of Erythema Nodosum Leprosum Possibly Triggered by COVID-19 Vaccine : A Case Repor. Indian Journal of Leprosy. 2022 Sep; 94: 275-278en_US
dc.identifier.issn0254-9395
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/222607
dc.languageenen_US
dc.publisherHind Kusht Nivaran Sangh (Indian Leprosy Association)en_US
dc.relation.volume94en_US
dc.source.urihttps://www.ijl.org.in/article-detail/94/431en_US
dc.subjectErythema Nodosum Leprosumen_US
dc.subjectAstraZeneca-Oxforden_US
dc.subjectCOVID-19 Vaccineen_US
dc.subjectLeprosyen_US
dc.subjectVaccinationen_US
dc.subjectType 2 Reactionen_US
dc.titleExacerbation of Erythema Nodosum Leprosum Possibly Triggered by COVID-19 Vaccine : A Case Reporen_US
dc.typeJournal Articleen_US
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