Environmental biotoxicity screening of some pyrrole and 1,4-dihydropyridine heterocyclic derivatives.

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dc.contributor.authorIdhayadhulla, A
dc.contributor.authorManilal, Aseer
dc.contributor.authorMerdekios, Behailu
dc.contributor.authorKumar, R Surendra
dc.date.accessioned2015-07-07T08:35:19Z
dc.date.available2015-07-07T08:35:19Z
dc.date.issued2015-05
dc.description.abstractSynthesis of pyrrole 1-3 and 1,4-dihydropyridine derivatives 4-6 were prepared from condensation method and synthesized compounds were screened for environmental biotoxicity such as Brine shrimp cytotoxicity, Ichthyotoxic, Larvicidal and Nematicidial activities. Among the compounds 3 and 6 shows that highly toxic (LD50: 8.72 and 12.30 μg/mL) against Brain shrimp cytotoxic screening and compound 3 and 6 was highly toxicity ( LD50 : 5.01 and 7.75 μg/mL) against Antifeedant screening (ichthyotoxic profile). The compounds 3 and 6 was highly active (LD50: 12.88 μg/mL, and 14.79 μg/mL) against Larvicidal activity and compound 3 and 6 was highly active (LD50 : 8.20 μg/mL, and 7.43 μg/mL) against Nematicidal activity.en_US
dc.identifier.citationIdhayadhulla A, Manilal Aseer, Merdekios Behailu, Kumar R Surendra. Environmental biotoxicity screening of some pyrrole and 1,4-dihydropyridine heterocyclic derivatives. Journal of Applied Pharmaceutical Science. 2015 May; 5(5): 101-105.en_US
dc.identifier.issn2231-3354
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/159224
dc.language.isoenen_US
dc.source.urihttps://www.japsonline.com/counter.php?aid=1518en_US
dc.subjectPyrrole derivativeen_US
dc.subject1en_US
dc.subject4-dihydropyridine derivativeen_US
dc.subjectBrine shrimp cytotoxicityen_US
dc.subjectIchthyotoxic screeningen_US
dc.subjectLarvicidal activityen_US
dc.subjectNematicidial activityen_US
dc.titleEnvironmental biotoxicity screening of some pyrrole and 1,4-dihydropyridine heterocyclic derivatives.en_US
dc.typeArticleen_US
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