Effect of oestrogen replacement therapy on bone mass in post-menopausal Bangladeshi women.

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dc.contributor.authorBegum, Fen_US
dc.contributor.authorShamsuddin, Len_US
dc.contributor.authorHussain, M Aen_US
dc.contributor.authorChowdhury, T Aen_US
dc.contributor.authorRahman, Men_US
dc.contributor.authorDas, T Ren_US
dc.date.accessioned2001-12-29en_US
dc.date.accessioned2009-05-27T03:47:09Z
dc.date.available2001-12-29en_US
dc.date.available2009-05-27T03:47:09Z
dc.date.issued2001-12-29en_US
dc.descriptionBangladesh Medical Research Council Bulletin.en_US
dc.description.abstractThe female population comprises 48.66% of our total population, of which 10.30% are above the age of 49, many of whom are post-menopausal. Menopause is associated with bone-loss and its consequences. Hormone replacement therapy (HRT), particularly replacement of estrogen, prevents bone-loss. We undertook this prospective case-controlled study to find out whether or not HRT is beneficial to our women. A total of 106 patients were studied, amongst them 60 were cases and 46 were controls. The women in the first group were given either conjugated equine estrogen alone (surgical menopause group) or conjugated equine estrogen plus cyclical progesterone (natural menopause group). Results showed that there was 4.29% increase in bone mineral density in women who received hormone replacement therapy (HRT). This increase was 5.23% in early and 3.56% in late menopause group. Women with natural menopause gained more bone mass (4.22%) than women with surgical menopause (3.9%). Our results also showed that women who denied HRT (controls) lost bone mass (5.26%), the loss was more in those with surgical menopause (6.24%) than those with natural menopause (4.87%). Therefore it can be concluded that post-menopausal hormone replacement therapy prevents bone-loss. However, to evaluate the beneficial effect of long-term HRT, further studies with larger samples are recommended.en_US
dc.description.affiliationDept. of Obst. & Gynae., Bangabandhu Sheikh Mujib Medical University, Dhaka.en_US
dc.identifier.citationBegum F, Shamsuddin L, Hussain MA, Chowdhury TA, Rahman M, Das TR. Effect of oestrogen replacement therapy on bone mass in post-menopausal Bangladeshi women. Bangladesh Medical Research Council Bulletin. 2001 Dec; 27(3): 103-11en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/325
dc.language.isoengen_US
dc.source.urihttps://www.banglajol.info/index.php/BMRCB/indexen_US
dc.subject.meshBangladeshen_US
dc.subject.meshBone Density --drug effectsen_US
dc.subject.meshBone and Bones --drug effectsen_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshEstrogen Replacement Therapyen_US
dc.subject.meshEstrogens --pharmacologyen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPostmenopauseen_US
dc.subject.meshProgesterone --pharmacologyen_US
dc.subject.meshProspective Studiesen_US
dc.titleEffect of oestrogen replacement therapy on bone mass in post-menopausal Bangladeshi women.en_US
dc.typeJournal Articleen_US
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