Selective cleavage of N-terminal amino acid in a peptide by polymeric cobalt (III) triene complex.
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1989-10-01
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Abstract
Cellulose was functionalized to incorporate triethylenetetramine group. This was in turn converted into the polymeric analogue of cobalt(III)triene complex. The polymeric complex reacts with peptides resulting in the cleavage of amino end amino acid, thus suggesting the applicability of the polymeric reagent as a solid phase reagent for N-terminal determination.
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Mehra A, Gupta SC, Narang CK, Mathur NK. Selective cleavage of N-terminal amino acid in a peptide by polymeric cobalt (III) triene complex. Indian Journal of Biochemistry & Biophysics. 1989 Oct; 26(5): 348-9