Hepatitis E epidemic with bimodal peak in a town of north India.

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dc.contributor.authorBali, Sen_US
dc.contributor.authorKar, S Sen_US
dc.contributor.authorKumar, Sen_US
dc.contributor.authorRatho, R Ken_US
dc.contributor.authorDhiman, R Ken_US
dc.contributor.authorKumar, Ren_US
dc.date.accessioned2008-10-05en_US
dc.date.accessioned2009-06-01T11:10:44Z
dc.date.available2008-10-05en_US
dc.date.available2009-06-01T11:10:44Z
dc.date.issued2008-10-05en_US
dc.description.abstractINTRODUCTION: An epidemic of viral hepatitis occurred in Mandi Gobindgarh town of Punjab in northern India during year 2005-06. An attempt was made to study the outbreak clinically, serologically, and etiologically. METHODS: Line listing and spot mapping of all cases of jaundice presented to civil hospital was done. An active search of cases was made through house-to-house visit with the help of 33 teams and 6 supervisors. Twenty two blood samples collected from acute cases were tested for anti-HAV IgM and anti-HEV IgM by ELISA. HEV specific PCR was also carried out. Sanitary survey was also done and water samples were tested for coliforms. RESULTS: In house to house survey 3170 cases of jaundice were reported; of them 2171 (68.5%) were males. Mean age was 28.8 years. Overall attack rate was 5.2%. The epidemic continued for more than a year and bimodal peak was observed. Civil hospital campus which has separate water supply had no jaundice case. About 95% blood samples from icteric patients were found to be positive for IgM and IgG antibodies of HEV. Eighteen persons died during the epidemic, mostly in old age group. Case fatality ratio was 0.57%. No deaths occurred among 17 pregnant women who had developed hepatitis. CONCLUSION: The epidemic was caused by hepatitis E virus, which was transmitted due to faecal contamination of municipal water supply.en_US
dc.description.affiliationDepartment of Community Medicine, M.L.N. Medical College, Allahabad University, Allahabad, U P India. drsurya72@yahoo.co.inen_US
dc.identifier.citationBali S, Kar SS, Kumar S, Ratho RK, Dhiman RK, Kumar R. Hepatitis E epidemic with bimodal peak in a town of north India. Indian Journal of Public Health. 2008 Oct-Dec; 52(4): 189-93, 199en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/110402
dc.language.isoengen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAge Distributionen_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 and overen_US
dc.subject.meshChilden_US
dc.subject.meshChild, Preschoolen_US
dc.subject.meshDisease Outbreaksen_US
dc.subject.meshFemaleen_US
dc.subject.meshHepatitis E --epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshIndia --epidemiologyen_US
dc.subject.meshInfanten_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshSex Distributionen_US
dc.subject.meshYoung Adulten_US
dc.titleHepatitis E epidemic with bimodal peak in a town of north India.en_US
dc.typeJournal Articleen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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