The role of Wobe-Mugos in reducing acute sequele of radiation in head and neck cancers--a clinical phase-III randomized trial.

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dc.contributor.authorKaul, Ren_US
dc.contributor.authorMishra, B Ken_US
dc.contributor.authorSutradar, Pen_US
dc.contributor.authorChoudhary, Ven_US
dc.contributor.authorGujral, M Sen_US
dc.date.accessioned2009-05-28T07:19:48Z
dc.date.available2009-05-28T07:19:48Z
dc.date.issued1999-06-02en_US
dc.description.abstractOral enzymes act as a potent antiinflammatory, antiedematous agents thereby decreasing acute toxigenic effect of radiation and increasing compliance, quality of life of our patients. Fifty patients were randomized 25 allocated in enzyme and radiotherapy arm, 25 in radiotherapy alone. Pre RT and post RT biopsies were taken from both arms. In our study it was found that there was clinical, histopathological as well as statistical significant difference in both arms. The enzyme arm patients had mucostis of grade I in 76%, grade II in 12%, grade III in 8% while as 8% had grade I, 68% grade II, 24% had grade III in RT arm alone. In enzyme patients skin reactions of grade I in 72%, 20% had grade II, 8% had grade III. In control arm 12% had grade I, 76% had grade II, 8% had grade III skin reaction.en_US
dc.description.affiliationDepartment of Radiotherapy, S.G.P.T. Cancer Hospital, Indore, M.P., India.en_US
dc.identifier.citationKaul R, Mishra BK, Sutradar P, Choudhary V, Gujral MS. The role of Wobe-Mugos in reducing acute sequele of radiation in head and neck cancers--a clinical phase-III randomized trial. Indian Journal of Cancer. 1999 Jun-Dec; 36(2-4): 141-8en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/51206
dc.language.isoengen_US
dc.source.urihttps://www.indianjcancer.comen_US
dc.subject.meshAcute Diseaseen_US
dc.subject.meshAdjuvants, Immunologic --administration & dosageen_US
dc.subject.meshAdministration, Oralen_US
dc.subject.meshAdulten_US
dc.subject.meshCarcinoma, Squamous Cell --radiotherapyen_US
dc.subject.meshChymotrypsinen_US
dc.subject.meshDrug Combinationsen_US
dc.subject.meshHead and Neck Neoplasms --radiotherapyen_US
dc.subject.meshHumansen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshMouth Mucosa --radiation effectsen_US
dc.subject.meshPancreatic Extracts --administration & dosageen_US
dc.subject.meshPapain --administration & dosageen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshRadiodermatitis --prevention & controlen_US
dc.subject.meshThymus Extracts --administration & dosageen_US
dc.subject.meshTrypsinen_US
dc.titleThe role of Wobe-Mugos in reducing acute sequele of radiation in head and neck cancers--a clinical phase-III randomized trial.en_US
dc.typeClinical Trialen_US
dc.typeClinical Trial, Phase IIIen_US
dc.typeJournal Articleen_US
dc.typeRandomized Controlled Trialen_US
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