A comparative study of serum lipid profile and gallstone disease.

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dc.contributor.authorAulakh, Rakhien_US
dc.contributor.authorMohan, Harshen_US
dc.contributor.authorAttri, A Ken_US
dc.contributor.authorKaur, Jasbinderen_US
dc.contributor.authorPunia, R P Sen_US
dc.date.accessioned2007-04-22en_US
dc.date.accessioned2009-05-29T11:43:10Z
dc.date.available2007-04-22en_US
dc.date.available2009-05-29T11:43:10Z
dc.date.issued2007-04-22en_US
dc.description.abstractThe diseased gallbladder is one of the commonest specimens submitted to the surgical pathology laboratory in North India. Obesity is associated with a linear increase in gallstone formation. It has been observed that the plasma lipoprotein profile of patients with gallstones differs markedly from that of healthy subjects. Serum lipid profile was done by enzyme kit method. All the gallstones received were categorized morphologically and examined biochemically. The age range of 200 cases was 13 to 77 years with a mean of43.75 +/- 13.39 years. There were 171 females (85.5%) and 29 males (14.5%) with male to female ratio of 1: 5.8. The stones containing both cholesterol and bile pigments were the most common (129 cases, 84.87%); while pure cholesterol stones were seen in 23 cases (11.50%) and pigment stones were infrequent (1 case, 0.65%). On lipidogram of patients in the study group, mean serum total cholesterol was 155.50 +/- 43.03 mg/dL, mean serum triglycerides was 100.49 +/- 45.23 mg/dL, mean HDL cholesterol was 46.71 +/- 15.20 mg/dL, mean LDL cholesterol was 87.94 +/- 36.85 mg/dL and mean VLDL cholesterol was 20.84 +/- 11.97 mg/dL. Serum total cholesterol values were significantly higher in patients older than 39 years as compared to patients < or =39 years (161.44 +/- 42.32 mg/dL vs. 145.79 +/- 32.96 mg/dL, p < 0.05). But the observed mean values in both of these subgroups were within the normal range i.e. <200 mg/dL. No significant difference was observed in the mean serum triglyceride values between male and female patients. The findings of this study did not indicate any role of serum lipid profile in the formation of gallstones. However the higher mean values of serum total cholesterol and serum triglycerides in patients older than 39 years of age may be explained by increasing age.en_US
dc.description.affiliationDepartment of Pathology, Govt. Medical College & Hospital, Chandigarh. rakhibatth@yahoo.comen_US
dc.identifier.citationAulakh R, Mohan H, Attri AK, Kaur J, Punia RP. A comparative study of serum lipid profile and gallstone disease. Indian Journal of Pathology & Microbiology. 2007 Apr; 50(2): 308-12en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/73820
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshBile Pigments --analysisen_US
dc.subject.meshCholesterol --analysisen_US
dc.subject.meshFemaleen_US
dc.subject.meshGallstones --blooden_US
dc.subject.meshHumansen_US
dc.subject.meshLipids --blooden_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.titleA comparative study of serum lipid profile and gallstone disease.en_US
dc.typeComparative Studyen_US
dc.typeJournal Articleen_US
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